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Erschienen in: Medical & Biological Engineering & Computing 8/2012

01.08.2012 | Review Article

Computational modeling of the human atrial anatomy and electrophysiology

verfasst von: Olaf Dössel, Martin W. Krueger, Frank M. Weber, Mathias Wilhelms, Gunnar Seemann

Erschienen in: Medical & Biological Engineering & Computing | Ausgabe 8/2012

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Abstract

This review article gives a comprehensive survey of the progress made in computational modeling of the human atria during the last 10 years. Modeling the anatomy has emerged from simple “peanut”-like structures to very detailed models including atrial wall and fiber direction. Electrophysiological models started with just two cellular models in 1998. Today, five models exist considering e.g. details of intracellular compartments and atrial heterogeneity. On the pathological side, modeling atrial remodeling and fibrotic tissue are the other important aspects. The bridge to data that are measured in the catheter laboratory and on the body surface (ECG) is under construction. Every measurement can be used either for model personalization or for validation. Potential clinical applications are briefly outlined and future research perspectives are suggested.

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Metadaten
Titel
Computational modeling of the human atrial anatomy and electrophysiology
verfasst von
Olaf Dössel
Martin W. Krueger
Frank M. Weber
Mathias Wilhelms
Gunnar Seemann
Publikationsdatum
01.08.2012
Verlag
Springer-Verlag
Erschienen in
Medical & Biological Engineering & Computing / Ausgabe 8/2012
Print ISSN: 0140-0118
Elektronische ISSN: 1741-0444
DOI
https://doi.org/10.1007/s11517-012-0924-6

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