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Studying the bactericidal ability and biocompatibility of gold and gold oxide nanoparticles decorating on multi-wall carbon nanotubes

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Multi-wall carbon nanotube (MWNT) was chemically oxidized by utilizing sulfuric and nitric acids in a ratio (2:1 v/v). The oxidized-MWNT was decorated with gold (Au) and gold oxide (Au2O3) nanoparticles by using precipitation approach. The Fourier transform infrared (FTIR) and zeta potential techniques verified oxidization of MWNTs with oxygen functional groups. The X-ray diffraction (XRD), ultraviolet–visible (UV–Vis) spectroscopy, and electron microscope were confirmed the coating of Au and Au2O3 nanoparticles onto MWNTs surface. The dual florescent assay and colony forming assay were used to assess antibacterial activity against Escherichia coli (E. coli) after incubation in the dark and under visible light exposure. Comparing with the raw-MWNTs and the oxidized-MWNTs, which were investigated to have poor bactericidal ability against E. coli, MWNTs/Au and MWNTs/Au2O3 revealed stronger bactericidal efficiency, essentially after photo-activation for 3 h. Moreover, MTT assay showed that the nanohybrids have higher cell viability than raw-MWNTs and the oxidized-MWNTs. The obtained results propose that nanohybrids were prepared as potent antibacterial materials to inhibit and control the persistence and spreading of microorganism diseases.

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Correspondence to Mustafa K. A. Mohammed.

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Ahmed, D.S., Mohammed, M.K.A. Studying the bactericidal ability and biocompatibility of gold and gold oxide nanoparticles decorating on multi-wall carbon nanotubes. Chem. Pap. 74, 4033–4046 (2020). https://doi.org/10.1007/s11696-020-01223-0

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  • DOI: https://doi.org/10.1007/s11696-020-01223-0

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