Abstract
Silver nanoparticles possess a wide range of applications especially in the field of medicine and this has stimulated the need for synthesizing them. Conventionally, chemical methods are used, which are hazardous and energy consuming. Therefore an eco-friendly and facile means of synthesizing nanoparticles is needed to replace the chemical method of synthesis. In the present study, silver nanoparticles were synthesized in a cost-effective and environment-friendly manner using aqueous leaf extract of Ailanthus excelsa—a medicinal tree used in the treatment of asthma, bronchitis, cold, abdominal pain, etc. The leaf extract helped in the bioreduction of silver ions yielding silver nanoparticles. The silver nanoparticles thus biosynthesized were characterized using UV–vis absorption spectroscopy, Fourier transform infrared spectroscopy (FTIR) analysis and scanning electron microscopy (SEM). These biologically synthesized silver nanoparticles were also found to exhibit excellent antibacterial effect against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumonia and anticancer effect against MCF-7 cell line.
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References
Devi H S and Singh T D 2014 Adv. Electron. Electr. Eng. 4 83
Rao Y N, Banerjee D, Datta A, Das S K, Guin R and Saha A 2010 Radiat. Phys. Chem. 79 1240
Makarov V V, Love A J, Sinitsyna O V, Makarova S S, Yaminsky I V, Taliansky M E and Kalinina N O 2014 Acta Naturae 6 20
Justin Packia Jacob S, Finub J S and Anand Narayanan P R 2012 Colloids Surf. B: Biointerfaces 91 212
Justin Packia Jacob S, Anand Narayanan P R and Finub J S 2013 World J. Pharm. Res. 2 1607
Haseeb H S and Justin Packia Jacob S 2014 World J. Pharm. Res. 3 792
Kumar D, Bhat Z A, Singh P, Shah M Y and Bhujbal S S 2010 Int. J. Pharmacol. 6 535
Jancy Mary E and Inbathamizh L 2012 Asian J. Pharma. Clin. Res. 5 0974
Mossman T 1983 J. Immunol. Methods 65 55
Singh A and Jain D 2010 Digest J. Nanomater. Biostruct. 5 483
Shameli K, Bin Ahmad M, Jaffar Al-Mulla E A, Ibrahim N A, Shabanzadeh P, Rustaiyan A, Abdollahi Y, Bagheri S, Abdolmohammadi S, Sani Usman M and Zidan M 2012 Molecules 17 8506
Anuj S A and Bishnava K 2013 Int. J. Pharma BioSci. 4 849
Lavhale M S and Mishra S H 2007 Pharmacognosy Rev. 1 105
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VINMATHI, V., PACKIA JACOB, S.J. A green and facile approach for the synthesis of silver nanoparticles using aqueous extract of Ailanthus excelsa leaves, evaluation of its antibacterial and anticancer efficacy. Bull Mater Sci 38, 625–628 (2015). https://doi.org/10.1007/s12034-015-0916-x
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DOI: https://doi.org/10.1007/s12034-015-0916-x