Abstract
Glasses based on the soda lime borophosphate system together with samples doped with SrO, ZnO or CuO were prepared. Glass – ceramic derivatives were prepared by controlled thermal heat – treatment with two step regime. All the prepared glasses and glass – ceramics were structurally characterized before and after immersion in phosphate solution (0.05 M %) for four weeks. X-ray diffraction and SEM investigations of the glass – ceramics were carried out to identify the formed crystalline species together with the morphological surface textures. The changes of the surface textures of the glasses and glass – ceramics were examined by SEM after immersion in phosphate solution. The full morphological examinations indicate that the hydroxyapatite crystalline phase is assumed to be formed after immersion of the glasses and glass- ceramics in phosphate solution. The two most distinctive parameters justifying the bioactivity of the glass or glass – ceramic samples studied are the appearance of the two far – IR peaks at about 550 and 650 cm−1 1 in the deconvoluted spectra after immersion in phosphate solution together with the simultaneous appearance of the rounded or nodular –shaped microcrystals as revealed by SEM images. These two features are known to be promising indicator as confirming the bioactivity of the studied glasses and glass-ceramics. The variations of dopants added are found to induce different effects on the micro-organisms and copper ions are retaining the most important active therapeutic elements for antimicrobial results.
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References
Hench LL (2006) The story of Bioglass. J Mater Sci Mater Med 967-978:17
Hench LL (2007) Breaking the biocompatibility barrier: development and application of bioactive materials. Imperial Colledge Press, London
Hench LL (1991) Bioceramic from concept to clinic. J Amer Ceram Soc 74(7):1487
Hench LL (1998) Bioceramics. J Amer Ceram Soc 81(7):1705
Hench LL (2011) Bioactive materials for gene control. In: Hench LL, Jones JR, Fenn MB (eds) New materials and technologies for healthcare. World Scientific, Singapore, pp 25–48
Hoppe A, Guldal NS, Boccaccini AR (2011) A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics. Biomaterials 32:2757–2774
Jones JR (2013) Review of bioactive glass: from Hench to hydrids. Acta Biomaterialia 9:4457–4486
Rahman MN, Day DE, Bal BS, Fu Q, Jung SB, Bonewald LF (2011) Bioactive glass in tissue engineering. Acta Biomater 7:2355–2373
Jung SB, Day DE, Stocker W, Taylor P (2011) Treatment of non-healing diabetic venous Stasis Ulters with bioactive glass nano fibers. Wound Repair Regen 19:A30
ElBatal FH, Ouis MA, ElBatal HA (2016) Comparative studies on the bioactivity of some borate glasses and glass-ceramics from the two systems: Na2,O-CaO-B2O3 and NaF-CaF2-B2O3. Ceramics Intern 42:8247–8256
Abou Neel EA, Pickup DM, Valappil SP, Newbort EJ, Knowles JC (2009) Bioactive functional materials: a perspective on phosphate-based glasses. J Mater Chem 19:690–701
Abdelghany AM, ElBatal FH, ElBatal HA (2014) Zinc containing borate glasses and glass-ceramics: search for biomedical applications. Process Appl Ceram 8(4):185–193
Marzouk MA, ElBatal HA (2014) In Vitro bioactivity of soda lime borate glasses with substituted SrO in sodium phosphate solution. Process Appl Ceram 8(3):167–177
Deliormanli AM (2014) In Vitro assessment of degradation and mineralization of V2O5 substituted borate bioactive glass. Scaffolds Mater Technol Adv Perform Mater 29(6):358–365
Abdelghany AM, Ouis MA, Azooz MA, El-Bassyouni GT (2016) Role of SrO on the bioactivit of some ternary borate glasses and their glass ceramic derivatives. Spectrochim Acta (A) 152:126–133
ElBata FH, El-Kheshen AA, El-Bassyouni GT, Abdel El-Aty A In Vitro bioactivity behavior of some borate glasses and their glass-Ceramic derivatives Containing Zn2+, Ag+ or Cu2+ by immersion in phosphate solution and their anti-Microbial activity. Silicon https://doi.org/10.1007/s12633-017-9552-Y
El-Sawy WS, Mohamed NA, Kassem EM, ElAty AA (2015) Res J Pharm Biol Chem Sci 6:213–224
Wong J, Angell CA (1976) Glass structure by spectroscopy. Marcel Dekker, New York
Moustafa YM, El-Egili K (1998) Infrared spectra of sodium phosphate glasses. J Non-Cryst Solids 240:144–153
Kamitsos EI (2003) Infrared studies of borate glasses. Phys Chem Glasses 44:79–89
Tarte P (1964) Identification of Li-O bands in the infrared spectra of simple lithium compounds containing LiO4 tetrahedra. Spectrochim Acta 20:238–240
Condrate R (1972) p.101 in : introduction to glass science. Plenum Press, New York
Abdelghany AM, ElBatal FH, Azooz MA, Ouis MA, ElBatal HA (2012) Optical and infrared Absorption spectra of 3d transition metal ions-doped sodium borophosphate glasses and effect of gamma irradiation. Spectrochim. Acta (A) 98:148–155
McMillan PW (1979) Glass-ceramics, 2nd edn. Academic Press, London
Holland W, Beall G (2002) Glass-ceramic technology, 2nd edn. American Ceramic Society, Westerville
Uhlmann DR, Shaw RR (1969) The thermal expansion of alkali borate glasses and the boric oxide anomaly. J Non-Cryst Solids 1:347
Hudon P, Buker DR (2002) The nature of phase separation in binary oxide melts and glasses. J Non-Cryst Soids 303:354
Kaur G, Waldrop SG, Kumar V, Pamdey OP, Sriranganathan N (2016). In: Marchi J (ed) Biocompatible glasses, advanced structural materials, vol 53. Springer International Publishing, Switzerland, pp 19–47, https://doi.org/10.1007/978-3-319-44249-5-2
Zhang D, Lepparanta O, Munkka E, Ylanen H, Viljanen MK, Eerole E (2010) Antibacterial effects and dissolution behavior of six bioactive glasses. Biomed Mater Res Part A 93A-475-483
Ye J, He J, Wang C, Yao K, Gom Z (2014) Biotechnol Lett 36:961–968
Goh YF, Alshemary AZ, Akram M, Abdulkader MR, Hussain R (2014) Intern J Appl Glass Sc 266:255–266
Bejarano J, Civredes P, Palza H (2015) Biomed Mater 10:025001
AbouNeel EA, Ahmed I, Pratten J, Nazhat SN, Knowles JC (2005) Characterization of antibacterial copper releasing degradable phosphate glass fibers. Biomaterials 26:2247–2254
Hoppe A, Meszaros R, Stähli C, Romies S, Schmidt J, Peukert W, Marelli B, Nazhat SN, Wondraczek L, Lao J, Jallot E, Boccaccinin AR (2013) In vitro reactivity of Cu-doped 45S4 Bioglass R derived scaffolds for bone tissue engineering. J Mater Chem B 1:5659–5674
Donnell MDO, Hill RG (2010) Influence of strontium and importance of glass chemistry and structure when desgining bioactive glasses for bone regeneration. Acta Biomater 6:2382–2385
Weil L, Ke J, Prasadam I, Misen RJ, Lin S, Xiao Y (2014) Osteoporous Int 25:2089–2096
Wu C, Fan W, Gelinsly M, Xiao Y, Simon P, Clwlze RS (2013) Acta Biomater 7:1797–1806
Ahmed I, Collins CA, Levis MP, Oslen I, Knowles JC (2004) Processing, characterization and biocompatibility of iron – phosphate glass fibers for tissue enginerring. Biomaterials 25:3223–3232
Bose S, Fielding G, Tarafder S, Bandyopadhyay A (2013) Trends Biotechnol 31:594–605
Yamaguchi M (2010) Mol Cell Biochem 338:241–254
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The authors of this work wish to express their gratitude to authorities of (National Research Centre, Egypt) for their financial support to conduct this work under project (No. 11090314).
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ElBatal, H.A., El-Kheshen, A.A., Ghoneim, N.A. et al. In Vitro Bioactivity Behavior of Some Borophosphate Glasses Containing Dopant of ZnO, CuO or SrO Together with their Glass-Ceramic Derivatives and their Antimicrobial Activity. Silicon 11, 197–208 (2019). https://doi.org/10.1007/s12633-018-9845-9
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DOI: https://doi.org/10.1007/s12633-018-9845-9