Skip to main content
Log in

MSDNet: a deep neural ensemble model for abnormality detection and classification of plain radiographs

  • Original Research
  • Published:
Journal of Ambient Intelligence and Humanized Computing Aims and scope Submit manuscript

A Correction to this article was published on 14 May 2022

This article has been updated

Abstract

Modern medical diagnostic techniques facilitate accurate diagnosis and treatment recommendations in healthcare. Such diagnostics procedures are performed daily in large numbers, thus, the clinical interpretation workload of radiologists is very high. Identification of abnormalities is a predominantly manual task that is performed by radiologists before the medical scans are available to the patient’s referring doctor for further recommendations. On the other hand, for a radiologist to delineate the imaging study’s findings/observations as a textual report is also a tedious task. Automated methods for radiographic image examination for identifying abnormalities and generating reliable radiology report are thus a fundamental requirement in clinical workflow management applications. In this work, we present an automated approach for abnormality classification, localization and diagnostic report retrieval for identified abnormalities. We propose MSDNet, an ensemble of Convolutional Neural models for abnormality classification, which combines the features of multiple CNN models to enhance abnormality classification performance. The proposed model also is designed to localize and visualize the detected abnormality on the radiograph image, based on an abnormal region detection algorithm to further optimize the diagnosis quality. Furthermore, the extracted features generated by MSDNet are used to automatically generate the diagnosis text report using an automatic content-based report retrieval algorithm. The upper extremity musculo-skeletal images from the MURA dataset and chest X-ray images from Indiana dataset were used for the experimental evaluation of the proposed approach. The proposed model achieved promising results, with an accuracy of 82.69%, showing its significant impact on alleviating radiologists’ cognitive load, thus improving the overall efficiency.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

Change history

Notes

  1. Receiver Operating Characteristic.

References

  • Aowal MA, Minhaz AT, Ashraf K (2017) Abnormality detection and localization in chest x-rays using deep convolutional neural networks. arXiv preprint arXiv:1705.09850

  • Baadjou VAE, Roussel NA, Verbunt JAMCF, Smeets RJEM, de Bie RA (2016) Systematic review: risk factors for musculoskeletal disorders in musicians. Occup Med 66(8):614–622

    Article  Google Scholar 

  • Banga D, Waiganjo P (2019) Abnormality detection in musculoskeletal radiographs with convolutional neural networks (ensembles) and performance optimization. arXiv preprint arXiv:1908.02170

  • BMUS (2014) United States Bone and Joint Initiative: The Burden of Musculoskeletal Diseases in the United States (BMUS), Fourth Edition. http://www.boneandjointburden.org/2014-report. [Accessed on 1 May 2019]

  • Chada G (2019) Machine learning models for abnormality detection in musculoskeletal radiographs. Rep Med Cases Images Videos 2(4):26

    Article  MathSciNet  Google Scholar 

  • Cheng C-T, Tsung-Ying H, Tao-Yi L, Chih-Chen C, Ching-Cheng C, I-Fang, Chien-Hung Liao, (2019) Application of a deep learning algorithm for detection and visualization of hip fractures on plain pelvic radiographs. Eur Radiol 29(10):5469–5477

    Article  Google Scholar 

  • Chung SW, Han SS, Lee JW, Kyung-Soo O, Kim NR, Yoon, et al (2018) Automated detection and classification of the proximal humerus fracture by using deep learning algorithm. Acta Orthop 89:4

    Article  Google Scholar 

  • Dalia Y, Bharath A, Mayya V, Sowmya Kamath S (2021) Deepoa: Clinical decision support system for early detection and severity grading of knee osteoarthritis. In 2021 5th International Conference on Computer, Communication and Signal Processing (ICCCSP), pages 250–255. IEEE

  • Demner-Fushman D, Kohli MD, Rosenman MB, Shooshan SE, Rodriguez L, Antani S, Thoma GR, McDonald CJ (2016) Preparing a collection of radiology examinations for distribution and retrieval. J Am Med Inform Assoc 23(2):304–310

    Article  Google Scholar 

  • Faes L, Wagner SK, Dun Jack F, Liu X et al (2019) Automated deep learning design for medical image classification by health-care professionals with no coding experience: a feasibility study. Lancet Digit Health 1(5):e232–e242

    Article  Google Scholar 

  • Gale W, Oakden-Rayner L, Carneiro G, Bradley AP, Palmer LJ (2017) Detecting hip fractures with radiologist-level performance using deep neural networks. arXiv preprint arXiv:1711.06504

  • García-Floriano A, Ferreira-Santiago Á, Camacho-Nieto O, Márquez C (2019) A machine learning approach to medical image classification: detecting age-related macular degeneration in fundus images. Comput Electr Eng 75:218–229

    Article  Google Scholar 

  • Harzig P, Chen YY, Chen F, Lienhart R (2019) Addressing data bias problems for chest x-ray image report generation. arXiv preprint arXiv:1908.02123,

  • He K, Zhang X, Ren S, Sun J (2016) Identity mappings in deep residual networks. In European conference on computer vision, pages 630–645. Springer

  • Ioppolo F, Rompe JD, Furia JP, Cacchio A (2014) Clinical application of shock wave therapy (swt) in musculoskeletal disorders. Eur J Phys Rehabil Med 50(2):217–30

    Google Scholar 

  • Karthik K, Sowmya Kamath S (2021) A deep neural network model for content-based medical image retrieval with multi-view classification. Vis Comput 37(7):1837–1850

    Article  Google Scholar 

  • Karthik K, Sowmya Kamath S (2021) Automated view orientation classification for x-ray images using deep neural networks. Smart computational intelligence in biomedical and health informatics. CRC Press, Boca Raton, pp 61–72

    Chapter  Google Scholar 

  • Katara K, Sowmya K et al (2021) Deep neural models for automated multi-task diagnostic scan management-quality enhancement, view classification and report generation. Biomed Phys Eng Express 8:1

    Google Scholar 

  • Kim DH, MacKinnon T (2018) Artificial intelligence in fracture detection: transfer learning from deep convolutional neural networks. Clin Radiol 73(5):439–445

    Article  Google Scholar 

  • Kitamura G, Chung CY, Moore BE (2019) Ankle fracture detection utilizing a convolutional neural network ensemble implemented with a small sample, de novo training, and multiview incorporation. J Digit Imaging 32(4):672–677

    Article  Google Scholar 

  • Krizhevsky A, Sutskever I, Hinton GE (2012) Imagenet classification with deep convolutional neural networks. Adv Neural Inf Process Syst 2:1097–1105

    Google Scholar 

  • Krogue Justin D, Cheng Kaiyang V, Hwang Kevin M, Paul T et al (2020) Automatic hip fracture identification and functional subclassification with deep learning. Radiol Artif Intell 2:2

    Google Scholar 

  • Krupinski EA, Berbaum KS, Caldwell RT, Schartz KM, Kim J (2010) Long radiology workdays reduce detection and accommodation accuracy. J Am Coll Radiol 7:9

    Article  Google Scholar 

  • Kumar A, Kim J, Lyndon D, Fulham M, Feng D (2016) An ensemble of fine-tuned convolutional neural networks for medical image classification. IEEE J Biomed Health Inform 21:1

    Google Scholar 

  • Mandikal V, Anantharaman A, Suhas BS (2019) An approach for multimodal medical image retrieval using latent dirichlet allocation. In Proceedings of the ACM India Joint International Conference on Data Science and Management of Data, pages 44–51

  • Mayya V, Karthik K, Sowmya KS, Karadka K, Jeganathan J (2021) Coviddx: Ai-based clinical decision support system for learning covid-19 disease representations from multimodal patient data. In HEALTHINF, pages 659–666

  • McHugh ML (2012) Interrater reliability: the kappa statistic. Biochem Med Biochem Med 22(3):276–282

    Article  MathSciNet  Google Scholar 

  • Mukesh BR, Harish T, Mayya V, Sowmya Kamath S (2021) Deep learning based detection of diabetic retinopathy from inexpensive fundus imaging techniques. In 2021 IEEE International Conference on Electronics, Computing and Communication Technologies (CONECCT), pages 1–6. IEEE

  • Nedumkunnel IM, George LE et al (2021) Explainable deep neural models for covid-19 prediction from chest x-rays with region of interest visualization. In 2021 2nd International Conference on Secure Cyber Computing and Communications (ICSCCC), pages 96–101. IEEE

  • Rajpurkar P, Irvin J, Bagul A, Ding D, Duan T et al (2017) Mura dataset: Towards radiologist-level abnormality detection in musculoskeletal radiographs. arXiv preprint arXiv:1712.06957

  • Rajpurkar P, Irvin J, Zhu K, Yang B, Mehta H et al (2017) Chexnet: Radiologist-level pneumonia detection on chest x-rays with deep learning. arXiv preprint arXiv:1711.05225

  • Saif AFM, Shahnaz C, Zhu WP, Omair AM (2019) Abnormality detection in musculoskeletal radiographs using capsule network. IEEE Access 7:81494–81503

    Article  Google Scholar 

  • Silvian SP, Maiya A, Resmi AT, Page T (2011) Antecedents of work related musculoskeletal disorders in software professionals. Int J Enterprise Netw Manag 4(3):247–260

    Article  Google Scholar 

  • Solovyova A, Solovyov I (2020) X-ray bone abnormalities detection using mura dataset. arXiv preprint arXiv:2008.03356

  • Soundalgekar P, Kulkarni M, Nagaraju D (2018) Medical image retrieval using manifold ranking with relevance feedback. In 2018 IEEE 12th International Conference on Semantic Computing (ICSC). IEEE,

  • Tataru C, Yi D, Shenoyas A, Ma A (2017) Deep learning for abnormality detection in chest x-ray images

  • Wærsted M, Hanvold TN, Veiersted KB (2010) Computer work and musculoskeletal disorders of the neck and upper extremity: a systematic review. BMC Musculoskelet Disord 11(1):79

    Article  Google Scholar 

  • Woolf AD, Pfleger B (2003) Burden of major musculoskeletal conditions. Bull World Health Organ 81:2

    Google Scholar 

  • Yahalomi F, Chernofsky M, Werman M (2019) Detection of distal radius fractures trained by a small set of x-ray images and faster r-cnn. In Intelligent Computing-Proceedings of the Computing Conference, pages 971–981. Springer,

  • Ying J, Dutta J, Guo N, Chenhui H, Zhou D, Sitek A, Li Q (2016) Classification of exacerbation frequency in the copdgene cohort using deep learning with deep belief networks. IEEE J Biomed Health Inform 2:2

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. Karthik.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest. This article does not contain any studies with human participants or animals performed by any of the authors and confirms that no ethical approval is required.

Data Availability Statement (DAS)

The datasets that were used and analyzed as part of the current study are openly and publicly available as: MURA datasethttps://stanfordmlgroup.github.io/competitions/mura/ and Indiana Datasethttps://www.kaggle.com/raddar/chest-xrays-indiana-university.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The original online version of this article was revised: “The missing images has been processed in table 2 of the original article”.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Karthik, K., Sowmya Kamath, S. MSDNet: a deep neural ensemble model for abnormality detection and classification of plain radiographs. J Ambient Intell Human Comput 14, 16099–16113 (2023). https://doi.org/10.1007/s12652-022-03835-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12652-022-03835-8

Keywords

Navigation