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Erschienen in: Demography 2/2013

01.04.2013

Estimation of Covariate Effects With Current Status Data and Differential Mortality

verfasst von: Alberto Palloni, Jason R. Thomas

Erschienen in: Demography | Ausgabe 2/2013

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Abstract

The assessment of the impact that socioeconomic determinants have on the prevalence of certain chronic conditions reported by respondents in population surveys must confront two problems. First, the self-reports could be in error (false positives and false negatives). Second, those reporting are a selected sample of those who ever experience the problem, and this selection is heavily influenced by excess mortality attributable to the condition being reported. In this article, we use a combination of empirical data and microsimulation to (a) assess the magnitude of the bias attributable to the selection problem, and (b) suggest an adjustment procedure that corrects for this bias. We find that the proposed adjustment procedure considerably reduces the bias arising from differential mortality.

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Fußnoten
1
See Weinberg et al. (1993, 1994) for research on the consequences of erroneously assuming stationarity when analyzing retrospective data.
 
2
Lin et al. (1998) studied the case of differential mortality and proposed a model for current-status data collected in an experimental setting in which all subjects are observed (and the monitoring time depends on the event of interest). We consider a different situation in which current-status data are randomly sampled from a population and differential mortality is more likely to prevent population members who experience the event of interest, relative to those who do not, from surviving to (and thus being observed at) the time of the survey (for individuals of a given age).
 
3
See Palloni and Thomas (2011) for an additional example concerning trends in the prevalence of disability in the United States.
 
4
The standard expression for SMAM is
https://static-content.springer.com/image/art%3A10.1007%2Fs13524-012-0160-6/MediaObjects/13524_2012_160_Equa_HTML.gif
where https://static-content.springer.com/image/art%3A10.1007%2Fs13524-012-0160-6/MediaObjects/13524_2012_160_Figbb_HTML.gif is the proportion single in the age group (x i , x i  + 1). This expression assumes that there is no marriage before age 15 or after age 50.
 
5
In what follows, risk homogeneity refers to a situation in which the risk of attrition before (and hence not being observed by) the time of a census or survey is independent of the event being studied. Conversely, risk heterogeneity is a situation in which precensus (survey) attrition occurs differentially among those who do and those who do not experience the event of interest.
 
6
Again, see Weinberg et al. (1993, 1994) for research on the consequences of erroneously assuming stationarity when analyzing retrospective data.
 
7
See Goldman (1993) for a simulation study of the roles of marital selection and marital protection in producing mortality differences between the married and single populations.
 
8
Results of simulated values of SMAM under different conditions are available on request.
 
9
See Palloni and Thomas (2011) for a derivation of these results from first principles.
 
10
To move from Eq. (1) to Eq. (2), combine the terms in the second factor involving https://static-content.springer.com/image/art%3A10.1007%2Fs13524-012-0160-6/MediaObjects/13524_2012_160_Fige_HTML.gif and note that the terms https://static-content.springer.com/image/art%3A10.1007%2Fs13524-012-0160-6/MediaObjects/13524_2012_160_Figf_HTML.gif and https://static-content.springer.com/image/art%3A10.1007%2Fs13524-012-0160-6/MediaObjects/13524_2012_160_Figg_HTML.gif combine to form the density function, which yields https://static-content.springer.com/image/art%3A10.1007%2Fs13524-012-0160-6/MediaObjects/13524_2012_160_Figh_HTML.gif —that is, the distribution function, when integrated.
 
11
If functional forms other than the logistic are deemed appropriate, the same conclusions about biases and inferential difficulties apply and only the functional form of the adjustment factor changes.
 
12
It is also worth noting that https://static-content.springer.com/image/art%3A10.1007%2Fs13524-012-0160-6/MediaObjects/13524_2012_160_Figv_HTML.gif , so 1 minus the estimated coefficient for the integrated hazard provides an estimate of the mortality difference between those with and without the disease.
 
13
We simulate growing birth cohorts simply to mimic real populations. All results apply if all rates of growth are set equal to zero, or if there are no calendar time effects on fertility, mortality, or the incidence of diabetes.
 
14
Although we started with a large number of simulations, a small number was enough to produce sufficient Monte Carlo variation. As a consequence, we settled on a total of 25 replicas.
 
15
Some researchers (e.g., Smith 2007) prefer to fit probit models to prevalence data to make inferences about incidence. We have not investigated the magnitude of the biases when the researcher estimates a probit rather than a logit model.
 
16
Recall that in the simulated data, this coefficient has a true value equal to 1.0.
 
17
In the sensitivity analysis, there is no mortality difference among the high-education group, but in the low-education group, mortality is 4.48 times higher among diabetics compared with nondiabetics. The mean errors are smaller than those presented in Fig. 5 when the mortality differential decreases.
 
18
Although these panel data can be used to obtain (noisy or error-ridden) estimates of diabetes incidence for any subgroup, we cannot do so before ages 50 (Mexico) or 60 (Puerto Rico). Because diabetes in these countries has a relatively early onset, the set of observed incidence rates is too incomplete to retrieve reliable effects of covariates. Additional information can be obtained online (http://​prehco.​rcm.​upr.​edu for PREHCO, and http://​www.​mhas.​pop.​upenn.​edu/​english/​home.​htm for MHAS).
 
19
Low education is defined as less than 6 years of schooling, and high education is defined as 6 years or more.
 
20
This is a refinement that we can introduce only due to the panel nature of the data.
 
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Metadaten
Titel
Estimation of Covariate Effects With Current Status Data and Differential Mortality
verfasst von
Alberto Palloni
Jason R. Thomas
Publikationsdatum
01.04.2013
Verlag
Springer US
Erschienen in
Demography / Ausgabe 2/2013
Print ISSN: 0070-3370
Elektronische ISSN: 1533-7790
DOI
https://doi.org/10.1007/s13524-012-0160-6

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