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Review on gold nanoparticles and their applications

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Abstract

Gold nanoparticles are widely used in many fields as preferred materials for their unique optical and physical properties, such as surface plasmon oscillations for labeling, imaging, and sensing. Recently, many advancements were made in biomedical applications with better biocompatibility in disease diagnosis and therapeutics. Au-NPs could be prepared and conjugated with many functionalizing agents, such as polymers, surfactants, ligands, dendrimers, drugs, DNA, RNA, proteins, peptides and oligonucleotides. This review addressed the use of gold nanoparticles and the surface functionalization with a wide range of molecules, expanding and improving gold nanoparticles in targeting drugs for photothermal therapy with reduced cytotoxic effcts in various cancers, gene therapy and many other diseases. Overall, Au-NPs would be a promising vehicle for drug delivery and therapies.

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Authors and Affiliations

  1. Department of BioNano Technology, Gachon University, Seongnam, 461-701, Korea

    Minakshi Das, Kyu Hwan Shim, Seong Soo A. An & Dong Kee Yi

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  1. Minakshi Das
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  2. Kyu Hwan Shim
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  3. Seong Soo A. An
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  4. Dong Kee Yi
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Correspondence to Seong Soo A. An or Dong Kee Yi.

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Das, M., Shim, K.H., An, S.S.A. et al. Review on gold nanoparticles and their applications. Toxicol. Environ. Health Sci. 3, 193–205 (2011). https://doi.org/10.1007/s13530-011-0109-y

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