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The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials

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Abstract

Background & objective(s)

The current evidence base regarding the impact of propolis consumption on lipid profile in humans is equivocal. Thus, we sought to investigate the impact of propolis consumption on anthropometric indices and lipid profile in this meta-analysis.

Methods

Cochrane Library, Scopus, PubMed, and Web of Science electronic databases were searched up to December 2019. A random-effects model used to pool effect size. The leave-one-out method used to conduct sensitivity analysis.

Results

Five RCTs were included in this study. Our findings indicated a significant decrease in triglyceride (TG) (WMD: −3.91 mg/dl, 95% CI: −4.22, −3.60), and a significant increase in high-density lipoprotein (HDL) (WMD: 3.41 mg/dl, 95% CI: 0.05, 6.76), however, for body mass index, weight, cholesterol (CL), and low-density lipoprotein (LDL), no significant alterations were evident.

Conclusion

This study revealed that consumption of propolis is associated with a reduction in TG levels, in addition to an increase in HDL levels. Nevertheless, additional research is required to further delineate the relationship between propolis consumption and lipid profile.

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Acknowledgments

This study is associated with project NO. 1398/10544 From Student Research Committee, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran. We are indebted to the Student Research Committee and Research & Technology Chancellor in SBMU for their financial support of this study.

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Authors and Affiliations

  1. Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Ammar Salehi-Sahlabadi

  2. Department of Pharmacy Practice, Indo-Soviet Friendship College of Pharmacy, Moga 142001, Punjab, India

    Manik Chhabra

  3. Department of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Jamal Rahmani

  4. Department of Physical Education and Sport Science, Humanity Faculty, Semnan University, Semnan, Iran

    Aref Momeni

  5. College of Pharmacy, Dalhousie University, Halifax, Canada

    Giorgio Karam

  6. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

    Elyas Nattagh-Eshtivani

  7. Students’ Research Committee, School of Nutrition and Food Science, Shiraz University of Medical Sciences, Shiraz, Iran

    Mehran Nouri

  8. Centre for Intelligent Healthcare, Coventry University, Coventry, UK

    Cain Clark

  9. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Pantea Salehi & Azita Hekmatdoost

Authors
  1. Ammar Salehi-Sahlabadi
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Correspondence to Azita Hekmatdoost.

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Salehi-Sahlabadi, A., Chhabra, M., Rahmani, J. et al. The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials. J Diabetes Metab Disord 19, 1835–1843 (2020). https://doi.org/10.1007/s40200-020-00604-2

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  • DOI: https://doi.org/10.1007/s40200-020-00604-2

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