Elsevier

Clinica Chimica Acta

Volume 5, Issue 4, July 1960, Pages 453-459
Clinica Chimica Acta

The estimation of thyroxine in human plasma by an electrophoretic technique

https://doi.org/10.1016/0009-8981(60)90051-6Get rights and content

Abstract

A new method for the determination of thyroxine in blood is described. It relies upon the quantitative dependence of the distribution of thyroxine between albumin and thyroxine-binding protein when exogenous 131I-labelled thyroxine is added to serum in vitro. Preliminary results suggest an accuracy in the estimate of the hormone of about 5–10%. Results in a group of patients whose plasma P.B.I, levels were also determined are given and shown to be similar.

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