Modulation of protein structure and function by asparagine-linked glycosylation

doi:10.1016/S1074-5521(96)90064-2

Chemistry & Biology

Volume 3, Issue 10, October 1996, Pages 803-812

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In eukaryotic cells, many enzymes are devoted to the construction of the complex glycan structures that decorate secreted and cell-surface proteins. Recent studies have begun to elucidate the effects of asparagine-linked glycosylation on protein folding and on the structure and function of mature glycoproteins.