Original investigationThe Role of Parallel Diffusion-Weighted Imaging and Apparent Diffusion Coefficient (ADC) Map Values for Evaluating Breast Lesions: Preliminary Results
Section snippets
Materials and methods
This was a retrospective study, and the Ethics Committee of our institution approved the study protocol. All subjects gave written informed consent before beginning the study.
Image artifacts
Among the 16 lesions in 16 patients studied, 3 lesions displayed distortion. The ADC values could not be measured in two of the three lesions. However, the distortion of normal breast tissue and lesions were reduced by ASSET-DWI, and artifacts resulting from ASSET around the breast did not influence the diagnostic ability of lesion visualization (Fig 1).
SNR and CNR
Because of distortion, the signals of two lesions could not be measured, so the CNR of 14 lesions were analyzed. The SNR of normal breast
The Study Demonstrated that using ASSET-DWI Decreased Known EPI Distortions and Provided Excellent Differentiation of Malignant from Benign Lesions
The usefulness of DWI has been established in the fields of neuroradiology (8) and in breast 12, 13, 14, 15, 16, 17, as mentioned in the introduction. However, traditional EPI-DWI has the disadvantages of susceptibility and phase encoding artifacts, such as chemical shift and ghosting. Parallel imaging techniques such as SENSE and ASSET, are the latest advancements in MRI technology, and they enable faster image acquisition time by reducing the number of phase-encoding steps. Our study
Conclusions
ASSET-DWI can be used to evaluate breast tissue with decreased distortion, susceptibility to artifacts, and acquisition time compared to other methods. The use of DWI is feasible and offers increased specificity with b values ranging from 600 to 1000 s/mm2. ADC map values of breast lesions can be used to further characterize malignant lesions from benign ones.
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2015, Egyptian Journal of Radiology and Nuclear MedicineCitation Excerpt :Kawashima et al. (23) and Hatakenaka et al. (24) concluded that a carcinoma with a very high signal intensity on T2-weighted images such as mucinous colloid carcinoma resulted in misleading ADC values because of a lower cell density and higher extracellular water content. Furthermore Guangwei et al. (25) and Woodhams et al. (26) also reported that most intraductal papilloma had low ADC values. Pereira et al. (15) showed that a malignant tumor with low cellularity, such as the malignant phyllodes tumor with cystic areas shows high ADC value, consequently was misdiagnosed as benign, Conversely, a benign tumor with high cellularity, such as the papilloma showed low ADC and led to the misdiagnosis of malignancy.
Breast DWI at 3 T: Influence of the fat-suppression technique on image quality and diagnostic performance
2015, Clinical RadiologyCitation Excerpt :Differences in DWI pulse sequence parameters or the use of different fat-suppression methods prevent a direct comparison between studies. Using PI, lower SNR and CNR had been reported by Jin et al.16 To isolate the effect of the fat-suppression technique, all other acquisition parameters were kept as constant as possible. DWI-SPAIR showed higher SNR and CNR than -STIR.
Diffusion-weighted breast imaging at 3 T: Preliminary experience
2014, Clinical RadiologyCitation Excerpt :Changes in mobility are reflected as differences in the signal intensity (SI) and can be quantified using the apparent diffusion coefficient (ADC), expressed as × 10−3 mm2/s.12 Different studies have used DW-MRI to examine breast tissue, although mostly at 1.5 T.13–15 In keeping with histological features, ADCs of malignant and benign lesions have been shown to differ, with values comparatively lower for malignant lesions.9,10,16,17 However, few prospective quantitative studies have been undertaken using 3 T equipment, which may provide added benefits.
This work was supported in part by NIH 1R01CA100184.