Bioactive Materials

Bioactive Materials

Volume 6, Issue 8, August 2021, Pages 2535-2545
Bioactive Materials

Self-adhesive lubricated coating for enhanced bacterial resistance

https://doi.org/10.1016/j.bioactmat.2021.01.028Get rights and content
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Highlights

  • A dopamine-assisted codeposition method was developed to prepare self-adhesive biomimetic lubricated coating.

  • The interfacial lubrication mechanism of the self-adhesive biomimetic coating was based on hydration lubrication.

  • The bacterial resistance mechanism of the biomimetic coating was investigated by force measurements on the nanoscale.

Abstract

Limited surface lubrication and bacterial biofilm formation pose great challenges to biomedical implants. Although hydrophilic lubricated coatings and bacterial resistance coatings have been reported, the harsh and tedious synthesis greatly compromises their application, and more importantly, the bacterial resistance property has seldom been investigated in combination with the lubrication property. In this study, bioinspired by the performances of mussel and articular cartilage, we successfully synthesized self-adhesive lubricated coating and simultaneously achieved optimal lubrication and bacterial resistance properties. Additionally, we reported the mechanism of bacterial resistance on the nanoscale by studying the adhesion interactions between biomimetic coating and hydrophilic/hydrophobic tip or living bacteria via atomic force microscopy. In summary, the self-adhesive lubricated coating can effectively enhance lubrication and bacterial resistance performances based on hydration lubrication and hydration repulsion, and represent a universal and facial strategy for surface functionalization of biomedical implants.

Keywords

Dopamine
Lubrication
Biomimetic coating
Bacterial resistance
Self-adhesive

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1

These authors contributed equally to this work.