Abstract
The occurrence of indole alkaloids among secondary fungal metabolites was studied in species of the genus Aspergillus, isolated from soils that were sampled in various regions of Russia (a total of 102 isolates of the species A. niger, A. phoenicis, A. fumigatus, A. flavus, A. versicolor, A. ustus, A. clavatus, and A. ochraceus). Clavine alkaloids were represented by fumigaclavine B, which was formed by A. fumigatus. α-Cyclopiazonic acid was formed by isolates of A. fumigatus, A. flavus, A. versicolor, A. phoenicis, and A. clavatus. The occurrence of indole-containing diketopiperazine alkaloids was documented for isolates of A. flavus, A. fumigatus, A. clavatus, and A. ochraceus. No indole-containing metabolites were found among the metabolites of A. ustus or A. niger.
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REFERENCES
Betina, V., Mycotoxins. Productions, Isolation, Separation and Purification, Amsterdam: Elsevier, 1984.
Berestetskii, O.A., Fitotoksicheskie svoistva pochvennykh mikroorganizmov (Phytotoxic Properties of Soil Microorganisms), Leningrad: VNIISKhM, 1978.
Tutel'yan, V.A. and Kravchenko, L.V., Mikotoksiny (Mycotoxins), Moscow: Meditsina, 1985.
Cole, R.J. and Cox, R.H., Handbook of Toxic Fungal Metabolites, New York.: Academic, 1981.
Flieger, M., Wurst, M., and Shelby, R., Folia Microbiol., 1997, vol. 42, no.1, pp. 3-30.
Frisvad, J.C. and Filtenborg, O., Mycologia, 1989, vol. 81, no.6, pp. 837-861.
Litvinov, M.A., Metody izucheniya pochvennykh mikroskopicheskikh gribov (Methords for Studying Microscopic Fungi of Soil), Leningrad: Nauka, 1969.
Vinokurova, N.G., Reshetilova, T.A., Adanin, V.M., and Kozlovskii, A.G., Prikl. Biokhim. Mikrobiol., 1991, vol. 27, no.6, pp. 850-856.
Kozlovskii, A.G., Solov'eva, T.F., Bukhtiyarov, Yu.E., et al., Mikrobiologiya, 1990, vol. 59, no.4, pp. 601-608.
Kozlovskii, A.G., Vinokurova, N.G., Zhelifonova, V.P., et al., Mikrobiologiya, 1997, vol. 66, no.5, pp. 600-604.
Reshetilova, T.A. and Kozlovskii, A.G., Prikl. Biokhim. Mikrobiol., 1990, vol. 26, no.3, pp. 291-306.
Horn, B.W. and Dorner, J.W., Appl. Environ. Microbiol., 1999, vol. 65, no.4, pp. 1444-1449.
Yamamoto, Y. and Arai, K., The Alkaloids: Chemistry and Pharmacology, Brossi, A., Ed., New York: Academic, 1986, vol. 29, pp. 185-263.
Springer, J.P., Buchi, G., Kobbe B., et al., Tetrahedron Lett., 1977, no. 28, pp. 2403-2406.
Barrow, C.J., Cai, P., Snyder, J.K., et al., J. Org. Chem., 1993, vol. 58, no.22, pp. 6016-6021.
Williams, R.M., Stocking, E.M., and Sanz-Cervera, F.J., Topics in Current Chemistry, Berlin: Springer, 2000, vol. 209, pp. 98-173.
Steyn, P.S., Tetrahedron, 1973, vol. 29, no.1, pp. 107-120.
Birch, A.J. and Russel, R.A., Tetrahedron, 1972, vol. 28, no.11, pp. 2999-3008.
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Vinokurova, N.G., Khmel'nitskaya, I.I., Baskunov, B.P. et al. Occurrence of Indole Alkaloids among Secondary Metabolites of Soil Aspergillus Spp.. Applied Biochemistry and Microbiology 39, 192–196 (2003). https://doi.org/10.1023/A:1022598215599
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DOI: https://doi.org/10.1023/A:1022598215599