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Preparation, characterization and in vitro antitumoral activity of a nanosize liposome complex encapsulated polyoxotungstate K6H2[CoW11TiO40]

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Abstract

The nanosize liposome complex-encapsulated polyoxotungstate K6H2[CoW11TiO40] has been prepared and structurally characterized by i.r., u.v.–vis and e.s.r. spectra. The particle size of the liposome complex-encapsulated K6H2[CoW11TiO40], is distributed in two uncontinuous limits in which 98.9% of particles distributed in the limit of 62.8–76.7 nm, average diameter, is 69.4 nm. The result shows that the polyoxotungstate retains the parent structure after being encapsulated by liposome, and that liposomal encapsulation increase the antitumoral activity of the polyoxometalate.

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References

  1. J.T. Rhule, C.L. Hill and D.A. Judd, Chem. Rev., 98, 327 (1998).

    Google Scholar 

  2. N. Yamamoto, D. Schols, E. Declercq, Z. Debyser, R. Pauwels, J. Balzarini, H. Nakashima, M. Baba, M. Hosoya, R. Snoeck, J. Neyts, G. Andrie, B.A. Murrer, B. Theobald, G. Bossard, G. Henson, M. Abrans and D. Picker, Mol. Pharmacol., 42, 1109 (1992).

    Google Scholar 

  3. J.L. Samonte, PhD Thesis, Georgetown University, 1996; Diss. Abs. Int. B., 58, 168 (1997).

  4. X.H. Wang, J.F. Liu and M.T. Pope, J. Chem. Soc. Dalton. Trans., 1, 957 (2003).

    Google Scholar 

  5. X.H. Wang, J.F. Liu, O. Liu, Y.G. Cheng and M.T. Pope, J. Chem. Soc. Dalton. Trans., 1399 (2000).

  6. X.H. Wang, J.T. Liu, J.X. Li and J.F. Liu, Inorg. Chem. Commun., 4, 372 (2001).

    Google Scholar 

  7. X.H. Wang, J.F. Liu, J.X. Li, J.T. Liu, Y. Yong, M.B.L. and M.T. Pope, J. Inorg. Biol., 94, 279 (2003).

    Google Scholar 

  8. Y.G. Cheng and J.F. Liu, Synth. React. Inorg. Met.-Org. Chem., 27, 239 (1997).

    Google Scholar 

  9. M. Mezei and V. Gulasekharam, J. Pharm. Pharmacol., 34, 473 (1982).

    Google Scholar 

  10. K. Nomiya, M. Miqa, R. Kobaysh and M. Aiao, Bull. Chem. Soc. Jpn., 54, 2983 (1981).

    Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry, Northeast Normal University, Chang Chun, 130024, P.R. China

    Yong Yang, Jianghua He, Xiaohong Wang, Bin Li & Jingfu Liu

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  1. Yong Yang
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  2. Jianghua He
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  3. Xiaohong Wang
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  4. Bin Li
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  5. Jingfu Liu
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Yang, Y., He, J., Wang, X. et al. Preparation, characterization and in vitro antitumoral activity of a nanosize liposome complex encapsulated polyoxotungstate K6H2[CoW11TiO40]. Transition Metal Chemistry 29, 96–99 (2004). https://doi.org/10.1023/B:TMCH.0000014494.72867.c5

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  • DOI: https://doi.org/10.1023/B:TMCH.0000014494.72867.c5

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