Skip to main content
Log in

Regional Innovation Systems: General Findings and Some New Evidence from Biotechnology Clusters

  • Published:
The Journal of Technology Transfer Aims and scope Submit manuscript

Abstract

This paper focuses on interactive innovation. It starts by operationalising Regional Innovation in the context of multi-level governance. It shows how regional and external innovation interaction among firms and other innovation organizations is important for regional innovation potential. The ability to access and use funding for innovation support for regional firms and organizations is crucial for regional innovation promotion. Equity investment funding is more important than public funding, which tends to be cautious and otherwise risk avoiding, except in circumstances of market arrest or failure to develop. Regional systems of innovation are broader than single sectors or clusters but some of these will be strategically privileged recipients of policy support because of their growth performance or potential, rather than, as in the past, their uncompetitiveness. The paper devotes space to exploring biotechnology clustering from a regional innovation systems viewpoint, as an instance of rather strong sectoral, regional innovation systems capabilities, though integrated also to global knowledge supply and markets. Illustration is provided of the way such sectoral innovation systems work at local regional level by reference to cases from Cambridge, Massachusetts and Cambridge, England.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Amin, A.and D.Thomas, 1996, ‘The Negotiated Economy: State and Civic Institutions in Denmark’, Economy and Society 25, 255-281.

    Google Scholar 

  • Amin, A.and N.Thrift, 1994, ‘Living in the Global’, in A. Amin and N.Thrift (eds.), Globalization, Institutions and Regional Development in Europe, Oxford: Oxford University Press, pp.1-22.

    Google Scholar 

  • Asheim, B.T., 1996, ‘Learning Regions in a Globalised World Economy: Towards New Competitive Advantages of Industrial Districts?’ Paper Presented at the European Urban and Regional Studies Conference, Exeter.

  • Argyris, C.and D. Schon, 1978, Organisational Learning: A Theory of Action Perspective, Reading, MA: Addison-Wesley.

    Google Scholar 

  • Audretsch, D., 1998, ‘Agglomeration and the Location of Innovative Activity’, Oxford Review of Economic Policy 14, 18-29.

    Google Scholar 

  • Autio, E., 1998, ‘Evaluation of RTD in Regional Systems of Innovation’, European Planning Studies 6, 131-140.

    Google Scholar 

  • Best, M., 1999, ‘Cluster Dynamics in Theory and Practice, with Applications to Singapore/Johor and Penang Electronics’, Judge Institute of Management Studies, Cambridge University.

  • Best, M., 2000, ‘Silicon Valley and the Resurgence of Route 128: Systems Integration and Regional Innovation’, in J. Dunning (ed.), Regions, Globalization and the Knowledgebased Economy, Oxford: Oxford University Press.

    Google Scholar 

  • Best, M., 2001, The New Competitive Advantage, Oxford: Oxford University Press.

    Google Scholar 

  • Braczyk, H.-J., P. Cooke, and M. Heidenreich (eds.), 1998, Regional Innovation Systems-The Role of Governances in a Globalized World, London: UCL Press.

    Google Scholar 

  • Cooke, P.(ed. ), 1995, The Rise of the Rustbelt, London: UCL Press.

    Google Scholar 

  • Cooke, P., 2002, ‘Biotechnology Clusters as Regional, Sectoral Innovation Systems’, International Regional Science Review 25, 8-37.

    Google Scholar 

  • Cooke, P., M. Uranga, and G. Etxebarria, 1997, ‘Regional Innovation Systems: Institutional and Organizational Dimensions’, Research Policy 26, 475-491.

    Google Scholar 

  • Cooke, P., M. Uranga, and G. Etxebarria, 1998, ‘Regional Systems of Innovation: An Evolutionary Perspective’, Environment and Planning A 30, 1563-1584.

    Google Scholar 

  • Cooke, P. and K. Morgan, 1998, The Associational Economy: Firms, Regions and Innovation, Oxford: Oxford University Press.

    Google Scholar 

  • Cooke, P., P. Boekholt, and F. Tödtling, 2000, The Governance of Innovation in Europe: Regional Perspectives on Global Competitiveness, London: Pinter.

    Google Scholar 

  • Cookson, C.and D.P illing, 1999, ‘Biotech Trade Looks to US to Cure Confidence Crisis’, Financial Times September 9, 11.

  • Crevoisier, O., 1997, ‘Financing Regional Endogenous Development: The Role of Proximity Capital in the Age of Globalization’, European Planning Studies 5, 407-416.

    Google Scholar 

  • Department of Trade and Industry, 1999 Biotechnology Clusters, London: DTI.

    Google Scholar 

  • Dohse, D., 2000, ‘Technology Policy and the Regions: The Case of the BioRegio Contest’, Research Policy 29, 1111-1133.

    Google Scholar 

  • Dosi, G., 1988, ‘Sources, Procedures and Microeconomic Effects of Innovation’, Journal of Economic Literature 26, 1120-1271.

    Google Scholar 

  • Eastern Region Biotechnology Initiative, 1998, '98, Cambridge: ERBI.

    Google Scholar 

  • Eastern Region Biotechnology Initiative, 1999, ‘Background Information for Cambridge and Eastern Region Biotechnology Cluster’, mimeographed, Cambridge, ERBI.

    Google Scholar 

  • Edquist, C., 1997, ‘Introduction: Systems of Innovation Approaches-Their Emergence and Characteristics’, in C. Edquist (ed.), Systems of Innovation: Technologies, Institutions and Organizations, London: Pinter, pp. 1-35.

    Google Scholar 

  • Edquist, C.(ed. ), 1997, Systems of Innovation: Technologies, Institutions and Organisations, London: Pinter.

    Google Scholar 

  • Enright, M., 1996, ‘Regional Clusters and Economic Development: A Research Agenda’, in V. Staber, N. Schaefer, and B. Sharma (eds.), Business Networks: Prospects for Regional Development, Berlin: de Gruyter, pp. 190-214.

    Google Scholar 

  • Etkowitz, H. and L. Leydesdorff, 1997, Universities and the Global Knowledge Economy, London: Pinter.

    Google Scholar 

  • European Commission, 1995, The Green Paper on Innovation, Commission of the European Communities, Luxembourg.

    Google Scholar 

  • Florida, R., 1995, ‘The Industrial Transformation of the Great Lakes Region’, in P. Cooke (ed.), The Rise of the Rustbelt, London: UCL Press, pp. 162-176.

    Google Scholar 

  • Freeman, C., 1987, Technology Policy and Economic Performance-Lesson from Japan, London: Pinter.

    Google Scholar 

  • Freeman, C., 1994, ‘The Economics of Technical Change’, Cambridge Journal of Economics, 463-514.

  • Freeman, C., 1995, ‘The “National System of Innovation” in Historical Perspective’, Cambridge Journal of Economics 19, 5-24.

    Google Scholar 

  • Grabher, G., 1993, ‘The Weakness of Strong Ties: The Lock-in of Regional Development in the Ruhr Area’, in G. Grabher (ed.), The Embedded Firm: On the Socioeconomics of Industrial Networks, London: Routledge, pp. 255-277.

    Google Scholar 

  • Grabher, G. (ed. ), 1993, The Embedded Firm: On the Socio-Economics of Industrial Network, London: Routledge.

    Google Scholar 

  • Johnson, B., 1992, ‘Institutional Learning’, in B. Lundvall (ed.), National Systems of Innovation: Towards a Theory of Innovation and Interactive Learning, London: Pinter, pp. 23-44.

    Google Scholar 

  • Krugman, P., 1997, ‘Good News from Ireland: A Geographical Perspective’, in A. Gray (ed.), International Perspectives on the Irish Economy, Dublin: Indecon.

    Google Scholar 

  • Krugman, P., 1998, ‘What's New About the New Economic Geography?’ Oxford Review of Economic Policy 14, 7-17.

    Google Scholar 

  • Lundvall, B.(ed. ), (1992) National Systems of Innovation: Towards a Theory of Innovation and Interactive Learning, London: Pinter.

    Google Scholar 

  • Lundvall, B. and B. Johnson, 1994, ‘The Learning Economy’, Journal of Industry Studies 1, 23-41.

    Google Scholar 

  • Maillat, D., 1995, ‘Territorial Dynamic, Innovative Milieus and Regional Policy’, Entrepreneurship and Regional Development 7, 157-165.

    Google Scholar 

  • Malmberg, A. and P. Maskell, 1997, ‘Towards an Explanation of Regional Specialization and Industry Agglomeration’, European Planning Studies 5, 25-42.

    Google Scholar 

  • Nelson, R. (ed. ), 1993, National Innovation Systems-A Comparative Analysis, Oxford: Oxford University Press.

    Google Scholar 

  • North, D., 1993, ‘Institutions and Economic Performance’, in U. Mäki, B. Gustafsson and C. Knudsen (eds.), Rationality, Institutions and Economic Methodology, London: Routledge, pp. 242-264.

    Google Scholar 

  • Porter, M., 1998, On Competition, Cambridge: Harvard Business School Press.

    Google Scholar 

  • Rosenfeld, S., 1997, ‘Bringing Business Clusters into the Mainstream of Economic Development’, European Planning Studies 5, 3-23.

    Google Scholar 

  • Sabel, C., 1995, Experimental Regionalism and the Dilemmas of Regional Economic Policy in Europe, Paris: OECD.

    Google Scholar 

  • Sabel, C., H. Kern, and G. Herrigel, 1989, Collaborative Manufacturing: New Supplier Relations in the Automobile Industry and the Redefinition of the Industrial Corporation, Cambridge: MIT.

    Google Scholar 

  • Saxenian, A., 1994, Regional Advantage: Culture and Competition in Silicon Valley and Route 128, Cambridge: Harvard University Press.

    Google Scholar 

  • Scott, A., 1993, Technopolis: High Technology Industry and Regional Development in Southern California, Oxford: University of California Press.

    Google Scholar 

  • Segal, Quince, and Wicksteed, 1998, Cambridge Phenomenon Update, Cambridge: SQW.

    Google Scholar 

  • Smilor, R., G. Dietrich, and D. Gibson, 1993, ‘The Entrepreneurial University: The Role of Higher Education in the United States in Technology Commercialization and Economic Development’, International Social Science Journal 45, 1-11.

    Google Scholar 

  • Smith, K., 1997, ‘Economic Infrastructures and Innovation Systems’, in C. Edquist (ed.), Systems of Innovation, London: Pinter.

    Google Scholar 

  • Storper, M., 1995, ‘The Resurgence of Regional Economies, Ten Years After: The Region as a Nexus of Untraded Interdependencies’, European Urban and Regional Studies 2, 191-221.

    Google Scholar 

  • Storper, M. and A. Scott, 1995, ‘The Wealth of Regions: Market Forces and Policy Imperatives in Local and Global Context’, Futures 27, 505-526.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cooke, P. Regional Innovation Systems: General Findings and Some New Evidence from Biotechnology Clusters. The Journal of Technology Transfer 27, 133–145 (2002). https://doi.org/10.1023/A:1013160923450

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1013160923450

Keywords

Navigation