Abstract
WE have reported1 that the polysaccharide lentinan obtained from Lentinus edodes (Berk.) Sing. (a popular edible mushroom in Japan) had a strong antitumour activity against sarcoma 180 implanted subcutaneously in mice, and that almost complete regression of the tumours had been observed after ten doses of 1 mg/kg. Lentinan is a β-(1→3)-linked linear glucan having a molecular weight of 950,000–1,050,000 according to light scattering methods.
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References
Chihara, G., Maeda, Y., Hamuro, J., Sasaki, T., and Fukuoka, F., Nature, 222, 687 (1969).
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CHIHARA, G., HAMURO, J., MAEDA, Y. et al. Antitumour Polysaccharide derived Chemically from Natural Glucan (Pachyman). Nature 225, 943–944 (1970). https://doi.org/10.1038/225943a0
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DOI: https://doi.org/10.1038/225943a0
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