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Possible mechanism for the biological action of lithium

Abstract

IN spite of considerable early controversy it is now generally recognised that lithium has a favourable therapeutic effect on affective disorders and for some years lithium salts have been used with some degree of success in medical practice1,2. Curiously, in spite of the extreme simplicity of lithium as a drug, there is little understanding of its mode of action. In this article we outline a possible explanation.

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References

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FRAUSTO DA SILVA, J., WILLIAMS, R. Possible mechanism for the biological action of lithium. Nature 263, 237–239 (1976). https://doi.org/10.1038/263237a0

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