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Beyond Hofmeister

Nature Chemistry volume 6, pages 261–263 (2014)Cite this article

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Research efforts related to the Hofmeister series of salt ions have waxed and waned during its long and storied history. The past few decades have, however, witnessed a renaissance in its study, and the importance of the related solvation science is becoming ever more apparent.

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Figure 1: A commemorative plaque at the Medical Faculty of the Charles University in Prague reading (in Czech and German): “Professor Franz Hofmeister (1850–1922), who carried out research in this building, predicted that amino acids in proteins are connected by a peptide bond and, in 1888, derived the lyotropic (Hofmeister) series of ions.”
Figure 2: Distribution of sodium (green) and potassium (cyan) cations around aqueous HIV-protease displayed with a colour-coded electrostatic surface (blue, negative; red, positive).

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Authors and Affiliations

  1. Pavel Jungwirth is at Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 16610, Prague 6, Czech Republic,

    Pavel Jungwirth

  2. Paul S. Cremer is at Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA,

    Paul S. Cremer

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  1. Pavel Jungwirth
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  2. Paul S. Cremer
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Correspondence to Pavel Jungwirth or Paul S. Cremer.

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Jungwirth, P., Cremer, P. Beyond Hofmeister. Nature Chem 6, 261–263 (2014). https://doi.org/10.1038/nchem.1899

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