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An astrocyte TRP switch for inhibition

Are astrocytes merely housekeeping cells that maintain constant the environment of neurons or are they important for CNS information processing? Intense debate over the function of calcium signaling in astrocytes will increase with the discovery of a previously unknown mechanism by which astrocyte [Ca2+]i is regulated.

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Figure 1: Pathways regulating astrocyte [Ca2+]i.

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Correspondence to David Attwell.

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Clarke, L., Attwell, D. An astrocyte TRP switch for inhibition. Nat Neurosci 15, 3–4 (2012). https://doi.org/10.1038/nn.3010

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