Issue 2, 2010
From the journal:

Chemical Communications

Application of d6 transition metal complexes in fluorescence cell imaging

Vanesa Fernández-Moreira,a   Flora L. Thorp-Greenwooda  and  Michael P. Coogan*a  

* Corresponding authors

a Department of Chemistry, Cardiff University, Cardiff, Cymru/Wales, UK
E-mail: cooganmp@cf.ac.uk
Fax: +44 (0)2920874030
Tel: +44 (0)2920874066

Abstract

Luminescent d6 transition metal complexes have often been proposed as useful fluorophores for cell imaging due to their attractive photophysical attributes, but until very recently their actual applications have been scarce, and largely limited to ruthenium complexes in DNA and oxygen sensing. In the last few years, however, there has been an increasing number of reports of the design and application in cellular studies of a diverse range of Ir, Re and Ru complexes tailor-made for imaging applications. The design principles, uptake and cellular localisation of this new class of imaging agents are presented in context in this feature article.

Graphical abstract: Application of d6 transition metal complexes in fluorescence cell imaging

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Article information

DOI
https://doi.org/10.1039/B917757D
Article type
Feature Article
Submitted
28 Aug 2009
Accepted
15 Oct 2009
First published
12 Nov 2009

Chem. Commun., 2010,46, 186-202

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Application of d6 transition metal complexes in fluorescence cell imaging

V. Fernández-Moreira, F. L. Thorp-Greenwood and M. P. Coogan, Chem. Commun., 2010, 46, 186 DOI: 10.1039/B917757D

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