Issue 3, 2012

Multicolor core/shell silicananoparticles for in vivo and ex vivo imaging

Abstract

Biocompatible highly bright silica nanoparticles were designed, prepared and tested in small living organisms for both in vivo and ex vivo imaging. The results that we report here demonstrate that they are suitable for optical imaging applications as a possible alternative to commercially available fluorescent materials including quantum dots. Moreover, the tunability of their photophysical properties, which was enhanced by the use of different dyes as doping agents, constitutes a very important added value in the field of medical diagnostics.

Graphical abstract: Multicolor core/shell silica nanoparticles for in vivo and ex vivo imaging

Supplementary files

Article information

Article type
Paper
Submitted
27 Sep 2011
Accepted
07 Nov 2011
First published
12 Dec 2011

Nanoscale, 2012,4, 824-830

Multicolor core/shell silica nanoparticles for in vivo and ex vivo imaging

E. Rampazzo, F. Boschi, S. Bonacchi, R. Juris, M. Montalti, N. Zaccheroni, L. Prodi, L. Calderan, B. Rossi, S. Becchi and A. Sbarbati, Nanoscale, 2012, 4, 824 DOI: 10.1039/C1NR11401H

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