Issue 15, 2012
From the journal:

Nanoscale

Exocytosis of peptide functionalized gold nanoparticles in endothelial cells†

Dorota Bartczak,a   Simone Nitti,c   Timothy M. Millarb  and  Antonios G. Kanaras*a  

* Corresponding authors

a Institute for Life Sciences and Physics and Astronomy, Faculty of Physical and Applied Sciences, Highfield, University of Southampton, Southampton, UK
E-mail: a.kanaras@soton.ac.uk
Fax: +44 (0)2380593910
Tel: +44 (0)2380592466

b Faculty of Medicine, University of Southampton, Southampton, UK

c Instituto Italiano di Technologia, Via Morego 30, Genova, Italy

Abstract

We present the exocytosis profile of two types of peptide-coated nanoparticles, which have similar charge and size but different functionality. While one kind of particles appears to progressively exocytose, the other one has a more complex profile, suggesting that some of the particles are re-uptaken by the cells. Both types of particles retain their colloidal stability after exocytosis.

Graphical abstract: Exocytosis of peptide functionalized gold nanoparticles in endothelial cells

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Article information

DOI
https://doi.org/10.1039/C2NR31064C
Article type
Communication
Submitted
01 May 2012
Accepted
13 Jun 2012
First published
29 Jun 2012

Nanoscale, 2012,4, 4470-4472

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Exocytosis of peptide functionalized gold nanoparticles in endothelial cells

D. Bartczak, S. Nitti, T. M. Millar and A. G. Kanaras, Nanoscale, 2012, 4, 4470 DOI: 10.1039/C2NR31064C

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