Issue 3, 2014
From the journal:

RSC Advances

Stereoselective total synthesis of (+)-hyptolide†

Gowravaram Sabitha,*a   A. Raju,a   C. Nagendra Reddya  and  J. S. Yadava  

* Corresponding authors

a Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad 500 007, India
E-mail: gowravaramsr@yahoo.com, sabitha@iict.res.in
Fax: +91-40-27160512

Abstract

Stereoselective synthesis of the naturally occurring 6-membered lactone hyptolide 1 is described. The main feature of the synthesis is the utility of the hitherto unexplored alkyne fragment derived from commercially available 3-butyn-1-ol (homopropargylic alcohol).

Graphical abstract: Stereoselective total synthesis of (+)-hyptolide

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Article information

DOI
https://doi.org/10.1039/C3RA45042B
Article type
Paper
Submitted
12 Sep 2013
Accepted
04 Nov 2013
First published
05 Nov 2013

RSC Adv., 2014,4, 1496-1502

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Stereoselective total synthesis of (+)-hyptolide

G. Sabitha, A. Raju, C. N. Reddy and J. S. Yadav, RSC Adv., 2014, 4, 1496 DOI: 10.1039/C3RA45042B

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