Issue 26, 2015
From the journal:

Chemical Communications

Photosensitizer conjugated iron oxide nanoparticles for simultaneous in vitro magneto-fluorescent imaging guided photodynamic therapy†

Md Nafiujjaman,ab   Vishnu Revuri,ab   Md Nurunnabi,b   Kwang Jae Choc  and  Yong-kyu Lee*ab  

* Corresponding authors

a Department of Green Bioengineering, Korea National University of Transportation, Chungju 380-702, South Korea
E-mail: leeyk@ut.ac.kr

b Department of Chemical & Biological Engineering, Korea National University of Transportation, Chungju 380-702, South Korea

c Department of Otolaryngology, Head & Neck Surgery, The Catholic University of Korea, College of Medicine Uijeongbu St. Mary’s Hospital, Kyunggi-Do 480-717, Republic of Korea

Abstract

In this study, photosensitizer conjugated iron oxide nanoparticles were strategically designed and prepared for simultaneous PDT and dual-mode fluorescence/MR imaging. The MRI contrast agent Fe3O4 was modified by APTES to functionalize the surface and further to link with heparin–pheophorbide-A conjugates.

Graphical abstract: Photosensitizer conjugated iron oxide nanoparticles for simultaneous in vitro magneto-fluorescent imaging guided photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C4CC10444G
Article type
Communication
Submitted
31 Dec 2014
Accepted
13 Feb 2015
First published
13 Feb 2015

Chem. Commun., 2015,51, 5687-5690

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Photosensitizer conjugated iron oxide nanoparticles for simultaneous in vitro magneto-fluorescent imaging guided photodynamic therapy

M. Nafiujjaman, V. Revuri, M. Nurunnabi, K. Jae Cho and Y. Lee, Chem. Commun., 2015, 51, 5687 DOI: 10.1039/C4CC10444G

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