Issue 31, 2014
From the journal:

Organic & Biomolecular Chemistry

Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units†

Sujit Suwala  and  Thomas Kodadek*a  

* Corresponding authors

a Department of Chemistry and Cancer Biology, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
E-mail: Kodadek@scripps.edu

Abstract

Diketopiperazine (DKP) units are found in many bioactive small molecules. Here we report facile chemistry for incorporating diverse DKP units within peptoid and peptoid-like libraries made by solid-phase split and pool synthesis.

Graphical abstract: Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units

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Article information

DOI
https://doi.org/10.1039/C4OB00829D
Article type
Communication
Submitted
22 Apr 2014
Accepted
23 Jun 2014
First published
30 Jun 2014

Org. Biomol. Chem., 2014,12, 5831-5834

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Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units

S. Suwal and T. Kodadek, Org. Biomol. Chem., 2014, 12, 5831 DOI: 10.1039/C4OB00829D

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