Issue 82, 2014
From the journal:

RSC Advances

A simple and green approach for the synthesis of polyfunctionalized mono- and bis-dihydro-2-oxopyrroles catalyzed by trityl chloride†

Seyed Sajad Sajadikhah*a  and  Malek Taher Maghsoodloub  

* Corresponding authors

a Department of Chemistry, Payame Noor University, Iran
E-mail: sssajadi@pnu.ac.ir

b Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran

Abstract

A simple synthesis of ployfunctionalized mono- and bis-dihydro-2-oxopyrrole derivatives is described by one-pot multi-component reaction of amines, dialkyl acetylenedicarboxylates and formaldehyde in the presence of trityl chloride (10 mol%) at room temperature in EtOH. The features of this procedure are mild and green reaction conditions, good to high yields, short reaction times, high atom economy, operational simplicity and no need for column chromatography.

Graphical abstract: A simple and green approach for the synthesis of polyfunctionalized mono- and bis-dihydro-2-oxopyrroles catalyzed by trityl chloride

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Article information

DOI
https://doi.org/10.1039/C4RA06923D
Article type
Paper
Submitted
10 Jul 2014
Accepted
04 Sep 2014
First published
05 Sep 2014

RSC Adv., 2014,4, 43454-43459

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A simple and green approach for the synthesis of polyfunctionalized mono- and bis-dihydro-2-oxopyrroles catalyzed by trityl chloride

S. S. Sajadikhah and M. T. Maghsoodlou, RSC Adv., 2014, 4, 43454 DOI: 10.1039/C4RA06923D

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