Issue 9, 2015
From the journal:

Journal of Materials Chemistry A

An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability†

Fengyun Guo,a   Nü Wang,*ab   Li Wang,c   Lanlan Hou,a   Lan Ma,a   Jing Liu,a   Yuee Chen,a   Bingbing Fana  and  Yong Zhao*a  

* Corresponding authors

a Key Laboratory of Bioinspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bioinspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, Beijing 100191, China
E-mail: wangn@buaa.edu.cn, zhaoyong@buaa.edu.cn
Fax: +86-10-82317801

b Institute for Superconducting and Electronic Materials, University of Wollongong, North Wollongong, Australia

c Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China

Abstract

A strong PCL/PU (polycaprolactone/polyurethane) vascular graft was fabricated using electrospinning. By regulating the content of PCL, the composite scaffolds show an obvious mechanical enhancement with strength up to 69.95 MPa. Furthermore, the scaffolds exhibit high porosity, mechanical anisotropy, cell compatibility and cycle performance, which are important for tissue engineering applications.

Graphical abstract: An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability

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Article information

DOI
https://doi.org/10.1039/C4TA06845A
Article type
Communication
Submitted
12 Dec 2014
Accepted
20 Jan 2015
First published
21 Jan 2015

J. Mater. Chem. A, 2015,3, 4782-4787

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An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability

F. Guo, N. Wang, L. Wang, L. Hou, L. Ma, J. Liu, Y. Chen, B. Fan and Y. Zhao, J. Mater. Chem. A, 2015, 3, 4782 DOI: 10.1039/C4TA06845A

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