Issue 1, 2016

Stimuli-responsive nanoparticles from ionic cellulose derivatives

Abstract

Stimuli-responsive nanoparticles (NPs) based on sustainable polymeric feedstock still need more exploration in comparison with NPs based on synthetic polymers. In this report, stimuli-responsive NPs from novel ionic cellulose derivatives were prepared via a facile nanoprecipitation. Cellulose 10-undecenoyl ester (CUE) with a degree of substitution (DS) of 3 was synthesized by esterification of cellulose with 10-undecenoyl chloride. Then, CUE was modified by photo-induced thiol–ene reactions, in order to obtain organo-soluble ionic cellulose derivatives with DSs of ∼3, namely cellulose 11-((3-carboxyl)ethylthio)undecanoate (CUE–MPA), cellulose 11-((2-aminoethyl)thio)undecanoate (CUE–CA), cellulose 11-(2-(2-(diethylamino)ethyl)thio)undecanoate (CUE–DEAET) and cellulose 11-(2-(2-(dimethylamino)ethyl)thio)undecanoate (CUE–DMAET). CUE–MPA could be transformed into NPs with average diameters in the range of 80–330 nm, but these NPs did not show particular stimuli-responsive properties. Moreover, the dropping technique resulted in smaller NPs than a dialysis technique. Stable NPs with average diameters in the range of 90–180 nm showing pH-responsive and switchable sizes were obtained from CUE–DEAET and CUE–DMAET possessing tertiary amines using nanoprecipitation. Thus, altering the terminal functional groups will be a new approach to prepare stimuli-responsive cellulose-derived polymeric NPs.

Graphical abstract: Stimuli-responsive nanoparticles from ionic cellulose derivatives

Supplementary files

Article information

Article type
Paper
Submitted
27 Aug 2015
Accepted
18 Nov 2015
First published
19 Nov 2015
This article is Open Access
Creative Commons BY license

Nanoscale, 2016,8, 648-657

Stimuli-responsive nanoparticles from ionic cellulose derivatives

Y. Wang, T. Heinze and K. Zhang, Nanoscale, 2016, 8, 648 DOI: 10.1039/C5NR05862G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements