Issue 75, 2017, Issue in Progress

Multi-functional thermo-crosslinkable collagen-metal nanoparticle composites for tissue regeneration: nanosilver vs. nanogold

Abstract

Collagen–silver/gold biomimetic matrices were developed for cardiac tissue engineering. The incorporation of nanoparticles led to modifications in the 3D structure of the collagen matrices, with gold increasing the materials' viscosity by ≈4 times. Electrical conductivity was also enhanced upon addition of the nanoparticles. The materials promoted reparative macrophage migration and improved the proliferation and function of neonatal cardiomyocytes under electrical stimulation.

Graphical abstract: Multi-functional thermo-crosslinkable collagen-metal nanoparticle composites for tissue regeneration: nanosilver vs. nanogold

Supplementary files

Article information

Article type
Paper
Submitted
13 Aug 2017
Accepted
05 Oct 2017
First published
11 Oct 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 47704-47708

Multi-functional thermo-crosslinkable collagen-metal nanoparticle composites for tissue regeneration: nanosilver vs. nanogold

K. Hosoyama, M. Ahumada, C. D. McTiernan, J. Bejjani, F. Variola, M. Ruel, B. Xu, W. Liang, E. J. Suuronen and E. I. Alarcon, RSC Adv., 2017, 7, 47704 DOI: 10.1039/C7RA08960K

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