Issue 17, 1999

Highly regio- and enantio-selective rhodium-catalysed asymmetric hydroformylation without organic solvents

Abstract

High enantioselectivity and unprecedented high regioselectivity without the need for hazardous organic solvents are achieved in rhodium-catalysed asymmetric hydroformylation with the perfluoroalkyl-substituted ligand (R,S)-3-H2F6-BINAPHOS, whereby the substitution pattern of the ligand is crucial for its successful use in compressed carbon dioxide and for the increased regioselectivity.

Article information

Article type
Paper

Chem. Commun., 1999, 1663-1664

Highly regio- and enantio-selective rhodium-catalysed asymmetric hydroformylation without organic solvents

G. Franciò and W. Leitner, Chem. Commun., 1999, 1663 DOI: 10.1039/A904281D

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