The Oslo and Paris Commission (OSPAR) Guidelines for monitoring the biological effects of tributyltin compounds (TBT) were evaluated using data collected for preparation of a Celtic Seas Quality Status Report. Two types of survey were undertaken: broad scale, to determine wide impacts in coastal waters; and localised, around representative harbours to establish ranges of effect from recognised input points. This evaluation indicates that results from the broad scale surveys can be used to compare different areas of coastline. Nucella is widespread away from point sources although many individuals show some degree of imposex. Populations are generally not at risk. The localised surveys indicate that, in certain situations, the monitoring objectives can be met in the OSPAR Guidelines (subject to minor amendment). Criteria are identified for the selection of point sources suitable for monitoring under OSPAR Guidelines.