Issue 1, 2008
From the journal:

Natural Product Reports

Metabolic diversity of lichen-forming ascomycetous fungi: culturing, polyketide and shikimatemetabolite production, and PKS genes

Elfie Stocker-Wörgötter*a  

* Corresponding authors

a University of Salzburg, Department of Organismic Biology, Hellbrunner Str. 34, Salzburg, Austria
E-mail: elfriede.stocker@sbg.ac.at
Web: http://www.sbg.ac.at/pfl/stocker.htm
Fax: +43-662-8044-142
Tel: +43-662-8044-5509

Abstract

Covering: 2001 to 2007

Lichens are composite and symbiotic organisms. Biologically, they often have been interpreted as one organism (fungi and algae associated within a common thallus), but taxonomically as a life form of ascomycetous fungi; as the lichen-forming fungus or “mycobiont” has been, in most cases, classified as the dominant symbiotic partner. About 46% of the ascomycota are lichen-forming, however, about 2–3% of the lichen fungi are basidiomycota. Lichen-forming fungi produce a great variety of secondary metabolites, biosynthetically derived from the acetyl polymalonyl, mevalonic and shikimate pathways. Thus, secondary metabolites comprise a significant proportion of the lichen thallus dry weight (0.1–5% or even more). The majority of secondary lichen products are aromatic polyketides, and a number of them has been shown to exhibit marked biological activity.

Graphical abstract: Metabolic diversity of lichen-forming ascomycetous fungi: culturing, polyketide and shikimatemetabolite production, and PKS genes

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Article information

DOI
https://doi.org/10.1039/B606983P
Article type
Review Article
Submitted
20 Sep 2007
First published
23 Oct 2007

Nat. Prod. Rep., 2008,25, 188-200

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Metabolic diversity of lichen-forming ascomycetous fungi: culturing, polyketide and shikimatemetabolite production, and PKS genes

E. Stocker-Wörgötter, Nat. Prod. Rep., 2008, 25, 188 DOI: 10.1039/B606983P

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