Issue 4, 2008
From the journal:

Soft Matter

Nanomechanics of polymer gels and biological tissues: A critical review of analytical approaches in the Hertzian regime and beyond

David C. Lin*a  and  Ferenc Horkay*a  

* Corresponding authors

a Laboratory of Integrative and Medical Biophysics, National Institutes of Health, Bethesda, MD, USA
E-mail: lindavid@mail.nih.gov, horkay@helix.nih.gov

Abstract

We survey recent progress in the application of nanoindentation to characterize the local mechanical properties of polymer gels and biological tissues. We review the theories, analytical models based thereon, and data processing techniques commonly used to determine elastic properties of these classes of materials by instrumented nanoindentation. Examples from the testing of synthetic and biological gels are used to illustrate the limitations of existing theories and approaches. Emphasis is placed on the need for contact mechanics models that more accurately represent the large-strain behaviour of soft matter.

Graphical abstract: Nanomechanics of polymer gels and biological tissues: A critical review of analytical approaches in the Hertzian regime and beyond

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Article information

DOI
https://doi.org/10.1039/B714637J
Article type
Review Article
Submitted
21 Sep 2007
Accepted
17 Dec 2007
First published
05 Feb 2008

Soft Matter, 2008,4, 669-682

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Nanomechanics of polymer gels and biological tissues: A critical review of analytical approaches in the Hertzian regime and beyond

D. C. Lin and F. Horkay, Soft Matter, 2008, 4, 669 DOI: 10.1039/B714637J

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