Issue 17, 2009
From the journal:

Chemical Communications

Fluorescence resonance energy transfer between an anionic conjugated polymer and a dye-labeled lysozymeaptamer for specific lysozyme detection†

Jing Wanga  and  Bin Liu*a  

* Corresponding authors

a Department of Chemical & Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore
E-mail: cheliub@nus.edu.sg
Fax: +65-67791936
Tel: +65-65168049

Abstract

Surface charge switch of a 6-carboxyfluorescein (FAM) labeled lysozymeaptamer from negative to positive upon lysozyme binding triggers fluorescence resonance energy transfer (FRET) between an anionic conjugated polymer and the aptamer, which provides a convenient method for lysozyme detection in biological media with high sensitivity and selectivity.

Graphical abstract: Fluorescence resonance energy transfer between an anionic conjugated polymer and a dye-labeled lysozymeaptamer for specific lysozyme detection

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Article information

DOI
https://doi.org/10.1039/B820001G
Article type
Communication
Submitted
10 Nov 2008
Accepted
20 Jan 2009
First published
04 Mar 2009

Chem. Commun., 2009, 2284-2286

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Fluorescence resonance energy transfer between an anionic conjugated polymer and a dye-labeled lysozymeaptamer for specific lysozyme detection

J. Wang and B. Liu, Chem. Commun., 2009, 2284 DOI: 10.1039/B820001G

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