Issue 26, 2011

Biochemistry of anionic calix[n]arenes

Abstract

This review treats the biological properties of the various anionic calix[n]arenes, both as soluble forms and in the collodal state. The complexation of these molecules with amino-acids, peptides and proteins is discussed, as is their interaction with model membranes. The complexations with various Active Pharmaceutical Ingredients as complexes, for tamoxifen as solid state and colloidal structures, are treated in depth. Two sections deal with the direct biological action of the calix[n]arenes and their use as biosensors. A final section deals with the toxicity, in reality the lack of toxicity of the calix[n]arenes.

Graphical abstract: Biochemistry of anionic calix[n]arenes

Article information

Article type
Feature Article
Submitted
17 Mar 2011
Accepted
07 Apr 2011
First published
09 May 2011

Chem. Commun., 2011,47, 7303-7319

Biochemistry of anionic calix[n]arenes

F. Perret and A. W. Coleman, Chem. Commun., 2011, 47, 7303 DOI: 10.1039/C1CC11541C

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