Issue 18, 2012

Hydrogen peroxide and glucose biosensor based on silver nanowires synthesized by polyol process

Abstract

Silver nanowires synthesized through a polyol process using polyvinylpyrrolidone as protection (PVP-AgNWs) were used as a new electrode material for constructing a sensor. Hydrogen peroxide (H2O2) and glucose were used as analytes to demonstrate the sensor performance of the PVP-AgNWs. It is found that the PVP-AgNWs-modified glassy carbon electrode (PVP-AgNWs/GCE) exhibits remarkable catalytic performance toward H2O2 reduction. This sensor has a fast amperometric response time of less than 2 s and the catalytic current is linear over the concentration of H2O2 ranging from 20 μM to 3.62 mM (R = 0.998) with a detection limit of 2.3 μM estimated on a signal-to-noise ratio of 3. A glucose biosensor was constructed by immobilizing glucose oxidase (GOD) onto the surface of the PVP-AgNWs/GCE. The resultant glucose biosensor can be used for glucose detection in human blood serum with a sensitivity of 15.86 μA mM−1 cm−2 and good selectivity and stability.

Graphical abstract: Hydrogen peroxide and glucose biosensor based on silver nanowires synthesized by polyol process

Article information

Article type
Paper
Submitted
27 Mar 2012
Accepted
23 Jun 2012
First published
25 Jun 2012

Analyst, 2012,137, 4362-4367

Hydrogen peroxide and glucose biosensor based on silver nanowires synthesized by polyol process

X. Yang, J. Bai, Y. Wang, X. Jiang and X. He, Analyst, 2012, 137, 4362 DOI: 10.1039/C2AN35407A

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