Issue 20, 2013
From the journal:

Journal of Materials Chemistry B

Single-walled carbon nanotube coated antibacterial paper: preparation and mechanistic study†

Archana R. Deokar,a   Lih-Yuan Lin,b   Chun-Chao Changcd  and  Yong-Chien Ling*a  

* Corresponding authors

a Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan
E-mail: ycling@mx.nthu.edu.tw

b Department of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan

c Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan

d Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 11031, Taiwan

Abstract

Development of carbon nanotubes toward commercial antibacterial applications warrants the understanding of their interaction mechanism with bacterial cells. The antibacterial activity and mechanism of acid-functionalized single-walled carbon nanotube (AFSWCNT) coated paper was assessed for gram-positive Staphylococcus aureus and gram-negative Escherichia coli models of bacteria. Better activity towards gram-positive bacteria was observed, whereas the presence of an outer membrane makes gram-negative bacteria more resistant to cell membrane damage caused by AFSWCNTs. Based on measured cytoplasmic efflux materials of bacteria, X-ray photoelectron spectroscopy, and scanning transmission electron microscopy combined with electron energy-loss spectroscopy imaging studies, we found that the better antibacterial activity of AFSWCNTs toward gram-positive bacteria is attributed to not only direct physical contact and piercing action, but also molecular-scale interaction with surface functional groups of bacteria. The novel antibacterial mechanism of AFSWCNTs might bring a promising strategy to design new antibacterial materials against drug-resistant bacteria species.

Graphical abstract: Single-walled carbon nanotube coated antibacterial paper: preparation and mechanistic study

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Article information

DOI
https://doi.org/10.1039/C3TB20188K
Article type
Paper
Submitted
08 Feb 2013
Accepted
22 Mar 2013
First published
26 Mar 2013

J. Mater. Chem. B, 2013,1, 2639-2646

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Single-walled carbon nanotube coated antibacterial paper: preparation and mechanistic study

A. R. Deokar, L. Lin, C. Chang and Y. Ling, J. Mater. Chem. B, 2013, 1, 2639 DOI: 10.1039/C3TB20188K

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