Issue 38, 2013
From the journal:

Journal of Materials Chemistry B

Shape memory poly(ε-caprolactone)-co-poly(ethylene glycol) foams with body temperature triggering and two-way actuation†

Richard M. Baker,a   James H. Hendersona  and  Patrick T. Mather*a  

* Corresponding authors

a Syracuse Biomaterials Institute, The Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, USA
E-mail: ptmather@syr.edu
Tel: +1-315-443-8760

Abstract

We describe the fabrication of porous foams with shape memory triggering at body temperature. Employing a modified porogen-leaching technique, functionalized poly(ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) macromers are crosslinked via thiol–ene chemistry to generate highly porous foam scaffolds with shape memory capacity. The temperature at which shape change of these scaffolds occurs under hydrated conditions can be tuned both through control of the chemical composition and through deformation temperature during mechanical programming of the scaffolds. Uniquely, the foams exhibit reversible actuation in compression, which has not previously been demonstrated for foams. Our results indicate that PCL–PEG shape memory foams have potential as programmable scaffolds for tissue engineering, regenerative medicine, and the study of cell mechanobiology.

Graphical abstract: Shape memory poly(ε-caprolactone)-co-poly(ethylene glycol) foams with body temperature triggering and two-way actuation

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Article information

DOI
https://doi.org/10.1039/C3TB20810A
Article type
Communication
Submitted
06 Jun 2013
Accepted
19 Aug 2013
First published
19 Aug 2013

J. Mater. Chem. B, 2013,1, 4916-4920

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Shape memory poly(ε-caprolactone)-co-poly(ethylene glycol) foams with body temperature triggering and two-way actuation

R. M. Baker, J. H. Henderson and P. T. Mather, J. Mater. Chem. B, 2013, 1, 4916 DOI: 10.1039/C3TB20810A

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