Download PDF
Synthesis 1976; 1976(4): 209-236
DOI: 10.1055/s-1976-23994
review
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Methods for the Construction of the Indolizine Nucleus*

Takane UCHIDA* , Kiyoshi MATSUMOTO
  • *Department of Chemistry, Faculty of Education, Fukui University, Fukui 910, Japan
Further Information

Publication History

Publication Date:
03 April 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Methods for the synthesis of various types of indolizines and a characteristic selection of their aza analogues are described. The reactions involved are classified as (a) condensation reactions, (b) 1,3-dipolar cycloadditions, and (c) 1,5-dipolar cyclizations. 1. Synthesis of Indolizines by Condensation Reactions 1.1. Reactions of 2-Methylpyridine and its Derivatives with Acid Anhydrides (Scholtz Reaction) 1.2. Cyclizations of Quaternary Pyridinium Salts (Tschitschibabin Reaction) 1.3. Cyclizations of 3-(2-Pyridyl)-1-propanols and their Derivatives 1.4. Reactions of Heteroaromatic Nitrogen Compounds with Acetylenic and Olefinic Compounds 1.5. Miscellaneous Condensations 2. Synthesis of Indolizines by 1,3-Dipolar Cycloadditions 2.1. Reactions of Pyridinium and Related Heteroaromatic Ylids 2.2. Reactions of N-Iminopyridinium Ylids 2.3. Reactions of Miscellaneous 1,3-Dipoles 3. Synthesis of Indolizines by 1,5-Dipolar Cyclizations

      >