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Planta Med 1984; 50(5): 391-394
DOI: 10.1055/s-2007-969746
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Struktur der Triterpen-Sapogenine von Aesculus glabra1

Structure of Triterpene-Sapogenins of Aesculus glabra1 E. Aurada, J. Jurenitsch, W. Kubelka
  • Institut für Pharmakognosie der Universität Wien, Währinger Straße 25, A-1090 Wien
1 Herrn Prof. Dr. R. Hegnauer mit den besten Wünschen zum Geburtstag gewidmet
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Publication History

1984

1984

Publication Date:
26 February 2007 (online)

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Abstract

After extraction of coarsely ground seeds of Aesculus glabra Willd. with 80% methanol the saponin fraction was submitted to enzymatic and acid hydrolysis, giving qualitatively identical TLC-spectra of the sapogenins. For separation of the obtained sapogenins silica gel-columns with chloroform-methanol-water mixtures as mobile phases were employed. Five main components (genins G-A to G-E), identified as 21,22-diangeloyl-barringtogenol C, 21,22-diangeloyl-R1-barrigenol, 21-angeloyl-barringtogenol C, 22-angeloyl-R1-barrigenol and 21-angeloyl-R1 barrigenol have been isolated. Structure elucidation was accomplished by 1H-NMR and mass spectrometry of the genins, their acetates and several isopropyliden derivatives. The acid free sapogenins barringtogenol C and R1 barrigenol (G-F and G-G) were found and identified by thin layer chromatography.

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