Subgraphs and network motifs in geometric networks

Shalev Itzkovitz and Uri Alon
Phys. Rev. E 71, 026117 – Published 22 February 2005

Abstract

Many real-world networks describe systems in which interactions decay with the distance between nodes. Examples include systems constrained in real space such as transportation and communication networks, as well as systems constrained in abstract spaces such as multivariate biological or economic data sets and models of social networks. These networks often display network motifs: subgraphs that recur in the network much more often than in randomized networks. To understand the origin of the network motifs in these networks, it is important to study the subgraphs and network motifs that arise solely from geometric constraints. To address this, we analyze geometric network models, in which nodes are arranged on a lattice and edges are formed with a probability that decays with the distance between nodes. We present analytical solutions for the numbers of all three- and four-node subgraphs, in both directed and nondirected geometric networks. We also analyze geometric networks with arbitrary degree sequences and models with a bias for directed edges in one direction. Scaling rules for scaling of subgraph numbers with system size, lattice dimension, and interaction range are given. Several invariant measures are found, such as the ratio of feedback and feed-forward loops, which do not depend on system size, dimension, or connectivity function. We find that network motifs in many real-world networks, including social networks and neuronal networks, are not captured solely by these geometric models. This is in line with recent evidence that biological network motifs were selected as basic circuit elements with defined information-processing functions.

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  • Received 7 September 2004

DOI:https://doi.org/10.1103/PhysRevE.71.026117

©2005 American Physical Society

Authors & Affiliations

Shalev Itzkovitz and Uri Alon

  • Departments of Molecular Cell Biology and Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel 76100

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Issue

Vol. 71, Iss. 2 — February 2005

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