Dynamical model for the full stretching curve of DNA

Alessandro Fiasconaro and Fernando Falo
Phys. Rev. E 86, 032902 – Published 24 September 2012

Abstract

We present a phenomenological dynamical model able to describe the stretching features of the curve of DNA length vs applied force. As concerns the chain, the model is based on the discrete wormlike chain model with elastic modifications, which properly describes the elongation features at low and intermediate forces. The dynamics is developed under a double-well potential with a linear term, which, at high forces, accounts for the narrow transition present in the DNA elongation (overstretching). A quite good agreement between simulation and experiment is obtained.

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  • Received 27 April 2012

DOI:https://doi.org/10.1103/PhysRevE.86.032902

©2012 American Physical Society

Authors & Affiliations

Alessandro Fiasconaro1,2,* and Fernando Falo1,3

  • 1Departamento de Física de la Materia Condensada, Universidad de Zaragoza, 50009 Zaragoza, Spain
  • 2Instituto de Ciencia de Materiales de Aragón, CSIC–Universidad de Zaragoza, 50009 Zaragoza, Spain
  • 3Instituto de Biocomputación y Física de Sistemas Complejos, Universidad de Zaragoza, Zaragoza, Spain

  • *afiascon@unizar.es

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Vol. 86, Iss. 3 — September 2012

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