Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors

Nuria Teigell Beneitez; Jeroen Missinne; Jean Schleipen; Joke Orsel; Menno W. J. Prins; Geert Van Steenberge

doi:10.1117/12.2036072

20 February 2014 Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors

Nuria Teigell Beneitez, Jeroen Missinne, Jean Schleipen, Joke Orsel, Menno W. J. Prins, Geert Van Steenberge

Author Affiliations +

Proceedings Volume 8954, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI; 89540Q (2014) https://doi.org/10.1117/12.2036072
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field based biosensor. In the proposed biosensor concept, super-paramagnetic nanoparticles are used as optical contrast labels. The nanoparticles capture target molecules from a sample fluid and bind to the sensor surface with biological specificity. The surface-bound nanoparticles are then detected using frustration of an evanescent field. In the current paper we elaborate on the polymer waveguides which are used to generate a well-defined optical field for nanoparticle detection.

Citation Download Citation

Nuria Teigell Beneitez, Jeroen Missinne, Jean Schleipen, Joke Orsel, Menno W. J. Prins, and Geert Van Steenberge "Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors", Proc. SPIE 8954, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI, 89540Q (20 February 2014); https://doi.org/10.1117/12.2036072

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