Terahertz spectroscopic characterization of cancer cells

Tatiana Globus; Dan Theodorescu M.D.; Henry Frierson M.D.; Tatyana Khromova; Dwight Woolard

doi:10.1117/12.594391

1 April 2005 Terahertz spectroscopic characterization of cancer cells

Tatiana Globus, Dan Theodorescu M.D., Henry Frierson M.D., Tatyana Khromova, Dwight Woolard

Proceedings Volume 5692, Advanced Biomedical and Clinical Diagnostic Systems III; (2005) https://doi.org/10.1117/12.594391
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

This work presents the first demonstration of the characterization of cancer cells using Fourier Transform Infrared Spectroscopy (FTIR) technique in the low terahertz frequency range of 10-25 cm^-1 and shows how this technique can be used to discriminate between two types of cancer (prostate and bladder) in cell culture. Samples of cancer cells suspended in buffer solution with the ratio of dry material to liquid ~ 1:10 were prepared and measured. The work will serve as the foundation for future work defining specific spectra associated with different tumor histologies and tumor progression and metastasis.

Citation Download Citation

Tatiana Globus, Dan Theodorescu M.D., Henry Frierson M.D., Tatyana Khromova, and Dwight Woolard "Terahertz spectroscopic characterization of cancer cells", Proc. SPIE 5692, Advanced Biomedical and Clinical Diagnostic Systems III, (1 April 2005); https://doi.org/10.1117/12.594391

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