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Formation of organic-inorganic composite materials based on cellulose Acetobacter xylinum and calcium phosphates for medical applications

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Abstract

The formation of composites based on the cellulose Acetobacter xylinum and calcium phosphates has been investigated using X-ray diffraction, electron diffraction, electron microscopy, energy-dispersive analysis, and differential scanning calorimetry. It has been demonstrated that the planar morphology of calcium phosphate nanoparticles capable of interacting with nanofibrils of the cellulose matrix is an important factor providing interfacial contacts in the formation of organic-inorganic composite materials. It has been established that magnesium-containing calcium phosphates represent two-phase systems consisting of calcium magnesium phosphate Ca2.6Mg0.4(PO4)2 (whitlockite) and hydroxyapatite Ca5(PO4)3(OH). The biocompatibility of the composite materials based on two-phase calcium phosphate systems and the temperature range of their stability (∼20–250°C) determined by the thermal stability of the organic component have been investigated.

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Authors and Affiliations

  1. Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences, nab. Admirala Makarova 2, St. Petersburg, 199034, Russia

    D. P. Romanov & V. L. Ugolkov

  2. Institute of Macromolecular Compounds, Russian Academy of Sciences, Bol’shoi pr. 31, St. Petersburg, 199004, Russia

    Yu. G. Baklagina, G. N. Gubanova, V. K. Lavrent’ev, T. E. Sukhanova & A. K. Khripunov

  3. St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia

    A. A. Tkachenko

  4. Scientific Center of Anti-Infective Drugs, The Ministry of Public Health of the Republic of Kazakhstan, pr. Al-Farabi 75b, Almaty, 050060, Kazakhstan

    V. A. Sinyaev

Authors
  1. D. P. Romanov
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  2. Yu. G. Baklagina
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  3. G. N. Gubanova
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  4. V. L. Ugolkov
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  5. V. K. Lavrent’ev
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  6. A. A. Tkachenko
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  7. V. A. Sinyaev
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  8. T. E. Sukhanova
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  9. A. K. Khripunov
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Correspondence to D. P. Romanov.

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Original Russian Text © D.P. Romanov, Yu.G. Baklagina, G.N. Gubanova, V.L. Ugolkov, V.K. Lavrent’ev, A.A. Tkachenko, V.A. Sinyaev, T.E. Sukhanova, A.K. Khripunov, 2010, published in Fizika i Khimiya Stekla.

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Romanov, D.P., Baklagina, Y.G., Gubanova, G.N. et al. Formation of organic-inorganic composite materials based on cellulose Acetobacter xylinum and calcium phosphates for medical applications. Glass Phys Chem 36, 484–493 (2010). https://doi.org/10.1134/S1087659610040139

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  • DOI: https://doi.org/10.1134/S1087659610040139

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