Abstract.
Local minima and the saddle points separating them in the energy landscape are known to dominate the dynamics of biopolymer folding. Here we introduce a notion of a “folding funnel” that is concisely defined in terms of energy minima and saddle points, while at the same time conforming to a notion of a “folding funnel” as it is discussed in the protein folding literature.
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Klemm, K., Flamm, C. & Stadler, P. Funnels in energy landscapes. Eur. Phys. J. B 63, 387–391 (2008). https://doi.org/10.1140/epjb/e2008-00136-7
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DOI: https://doi.org/10.1140/epjb/e2008-00136-7