Sol–Gel-Derived Silicate Nano-Hybrids for Biomedical Applications

Kanji Tsuru; Yuki Shirosaki; Satoshi Hayakawa; Akiyoshi Osaka

doi:10.1248/bpb.b13-00526

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Sol–Gel-Derived Silicate Nano-Hybrids for Biomedical Applications

Kanji Tsuru, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka

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Keywords: hybrid, sol–gel, silane, natural polymer, bioreactor, nerve regeneration

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2013 Volume 36 Issue 11 Pages 1683-1687

DOI https://doi.org/10.1248/bpb.b13-00526

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Abstract

Organic–inorganic hybrids of poly(dimethyl siloxane), gelatin, and chitosan with such silanes as tetraethoxysilane and 3-glycidoxytriethoxysilane are derived via the sol–gel routes. Their biomedical applications are discussed from biomimetic deposition of bone-like apatite, cell culture, and in vivo behavior.

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