This paper suggests a material mixing method to mix several materials in a structure. This method is based on ESO (Evolutionary Structural Optimization), which has been used to optimize topology of only one material structure. In this study, two criterions for material transformation and element removal are implemented for mixing several materials in a structure. Optimal topology for a multiple material structure can be obtained through repetitive application of the two criterions at each iteration. Two practical design examples of a short cantilever are presented to illustrate validity of the suggested material mixing method. It is found that the suggested method works very well and a multiple material structure has more stiffness than one material structure has under the same mass.