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Licensed Unlicensed Requires Authentication Published by De Gruyter March 4, 2014

Level set method coupled with Energy Image features for brain MR image segmentation

  • Mirela (Visan) Punga , Rahul Gaurav and Luminita Moraru EMAIL logo

Abstract

Up until now, the noise and intensity inhomogeneity are considered one of the major drawbacks in the field of brain magnetic resonance (MR) image segmentation. This paper introduces the energy image feature approach for intensity inhomogeneity correction. Our approach of segmentation takes the advantage of image features and preserves the advantages of the level set methods in region-based active contours framework. The energy image feature represents a new image obtained from the original image when the pixels’ values are replaced by local energy values computed in the 3×3 mask size. The performance and utility of the energy image features were tested and compared through two different variants of level set methods: one as the encompassed local and global intensity fitting method and the other as the selective binary and Gaussian filtering regularized level set method. The reported results demonstrate the flexibility of the energy image feature to adapt to level set segmentation framework and to perform the challenging task of brain lesion segmentation in a rather robust way.


Corresponding author: Luminita Moraru, Faculty of Sciences and Environment, Department of Chemistry, Physics and Environment, Dunarea de Jos University of Galati, 47 Domneasca St., 800008 Galati, Romania, Phone: +40745649014, Fax: +40236461353, E-mail:

Acknowledgments

The authors would like to thank Dr. Adina-Geanina Nămoianu, St. Andrew Emergency Hospital, Galati, Romania, for useful discussions.

References

[1] Angelini ED, Song T, Mensh BD, Laine A. Segmentation an quantitative evaluation of the brain MRI data with a multi-phase three-dimensional implicit deformable model, In: Fitzpatrick JM, Sonka M, editors. Medical imaging: image processing. Proceedings of SPIE, vol 5370, Bellinham, WA 2004.10.1117/12.535860Search in Google Scholar

[2] Balafar MA, Ramli AR, Saripan MI, Mashohor S. Review of brain MRI image segmentation methods. Artif Intell Rev 2010; 33: 261–274.10.1007/s10462-010-9155-0Search in Google Scholar

[3] Chan TF, Vese LA. Active contours without edges. IEEE Trans Image Process 2001; 10: 266–277.10.1109/83.902291Search in Google Scholar PubMed

[4] Ciecholewski M, Chocholowicz J. Gallbladder shape extraction from ultrasound images using active contour models. Comput Biol Med 2013; 43: 2238–2255.10.1016/j.compbiomed.2013.10.009Search in Google Scholar PubMed

[5] Elter M, Held C, Wittenberg T. Contour tracing for segmentation of mammographic masses. Phys Med Biol 2010; 55: 5299–5315.10.1088/0031-9155/55/18/004Search in Google Scholar PubMed

[6] Eskildsen SF, Coupé P, Fonov V, et al. BEaST: brain extraction based on nonlocal segmentation technique. NeuroImage 2012; 59: 2362–2373.10.1016/j.neuroimage.2011.09.012Search in Google Scholar PubMed

[7] Li BN, Chui CK, Chang S, Ong SH. Integrating spatial fuzzy clustering with level set methods for automated medical image segmentation. Comput Biol Med 2011; 41: 1–10.10.1016/j.compbiomed.2010.10.007Search in Google Scholar PubMed

[8] Ma B, Wu Y, Li P. Level set segmentation using image second order statistics. In: Zhang T, editor. Automatic target recognition and image analysis. Proceedings of SPIE, vol 8003, Nong Sang, Guilin, China 2011.10.1117/12.902005Search in Google Scholar

[9] Mallikarjuna PB, Guru DS. Performance Evaluation of Segmentation and Classification of Tobacco Seedling Diseases. Int J Mach Intell 2011; 3: 204–211.Search in Google Scholar

[10] Mitchell IM. The flexible, extensible and efficient toolbox of level set methods. J Sci Comput 2008; 35: 300–329.10.1007/s10915-007-9174-4Search in Google Scholar

[11] Moraru L, Moldovanu S. Comparative study on performance of textural image features for active contour segmentation. Sci China Life Sci 2012; 55: 637–644.10.1007/s11427-012-4344-5Search in Google Scholar PubMed

[12] Mumford D, Shah J. Optimal approximation by piecewise smooth functions and associated variational problems. Commun Pure Appl Math 1989; 42: 577–685.10.1002/cpa.3160420503Search in Google Scholar

[13] Osher S, Sethian JA. Fronts propagating with curvature-dependent speed: algorithms based on Hamilton-Jacobi formulation. J Comput Phys 1988; 79: 12–49.10.1016/0021-9991(88)90002-2Search in Google Scholar

[14] Paragios N. A level set approach for shape-driven segmentation and tracking of left ventricle. IEEE Trans Med Imaging 2003; 22: 773–776.10.1109/TMI.2003.814785Search in Google Scholar PubMed

[15] Saad NM, Abu-Bakar SAR, Abdullah AR, Salahuddin L, Muda S, Mokji M. Brain Lesion segmentation from diffusion weighted MRI based on adaptive thresholding and gray level co-occurrence matrix. Journal of Telecommunication, Electronic and Computer Engineering 2011; 3: 1–14.Search in Google Scholar

[16] Schlaggar BL, Brown TT, Lugar HM, Visscher KM, Miezin FM, Petersen SE. Functional neuroanatomical differences between adults and school-age children in processing of single words. Science 2002; 296: 1476–1479.10.1126/science.1069464Search in Google Scholar PubMed

[17] Schmidt P, Gaser C, Arsic M, et al. An automated tool for detection of FLAIR-hyperintense white-matter lesions in multiple sclerosis. NeuroImage 2012; 59: 3774–3783.10.1016/j.neuroimage.2011.11.032Search in Google Scholar PubMed

[18] Shattuck DW, Prasad G, Mirza M, Narr KL, Toga AW. On line resource for validation of brain segmentation methods. NeuroImage 2009; 45: 431–439.10.1016/j.neuroimage.2008.10.066Search in Google Scholar PubMed PubMed Central

[19] Suri JS, Liu K, Singh S, Laxminarayan SN, Zeng X, Reden L. Shape recovery algorithms using level sets in 2-D/3-Dmedical imagery: a state-of-the-art review. IEEE Trans Inf Technol Biomed 2002; 6: 8–28.10.1109/4233.992158Search in Google Scholar PubMed

[20] Wang L, He L, Mishra A, Li C. Active contours driven by local Gaussian distribution fitting energy. Signal Process 2009; 89: 2435–2447.10.1016/j.sigpro.2009.03.014Search in Google Scholar

[21] Wang L, Li C, Sun Q, Xia D, Kao C-Y. Active contours driven by local and global intensity fitting energy with application to brain MR image segmentation. Comput Med Imaging Graph 2009; 33: 520–531.10.1016/j.compmedimag.2009.04.010Search in Google Scholar PubMed

[22] Wang L, Shi F, Lin W, Gilmore JH, Shen D. Automatic segmentation of neonatal images using convex optimization and coupled level sets. NeuroImage 2011; 58: 805–817.10.1016/j.neuroimage.2011.06.064Search in Google Scholar PubMed PubMed Central

[23] Zhang K, Zhang L, Song H, Zhou W. Active contours with selective local or global segmentation: a new formulation and level set method. Image Vision Comput 2010; 28: 668–676.10.1016/j.imavis.2009.10.009Search in Google Scholar

Received: 2013-10-17
Accepted: 2014-2-10
Published Online: 2014-3-4
Published in Print: 2014-6-1

©2014 by Walter de Gruyter Berlin/Boston

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