Skip to main content
SpringerLink
Log in

Evaluation of a Hydrophilic Ionic Liquid as a Salting-out Phase Separation Agent to a Water-Tetrahydrofuran Homogeneous System for Aqueous Biphasic Extraction Separation

  • Rapid Communications
  • Published:
Analytical Sciences Aims and scope Submit manuscript

Abstract

The use of a hydrophilic ionic liquid (IL), 1-butyl-3-methylimidazolium chloride (C4mimCl), as a salting-out phase separation agent to a water–tetrahydrofuran homogeneous system was studied for possible applications to novel aqueous biphasic extraction separation. The IL showed a salting-out phase-separation ability. Also, differences in the polarity between the formed two phases were smaller than that when using NaCl as a salting-out agent. This result suggested that C4mimCl remaining in water-rich phase acts not only as a salting-out agent, but also a component of a mixed-solvent. Possible uses of C4mimCl/NaCl mixed salting-out agent system were also discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. C. F. Poole and S. K. Poole, J. Chromatogr., A, 2010, 1217, 2268, and references therein.

  2. E. M. Martinis, P. Berton, R. P. Monasterio, and R. G. Wuilloud, Trends Anal. Chem., 2010, 29, 1184, and references therein.

  3. N. Hirayama, Solvent Extr. Res. Dev., Jpn., 2011, 18, 1, and references therein.

  4. K. E. Gutowski, G. A. Broker, H. D. Willauer, J. G. Huddleston, R. P. Swatloski, J. D. Holbrey, and R. D. Rogers, J. Am. Chem. Soc., 2003, 125, 6632.

    Article  CAS  PubMed  Google Scholar 

  5. S. Li, C. He, H. Liu, K. Li, and F. Liu, J. Chromatogr., B, 2005, 826, 58.

    Article  CAS  Google Scholar 

  6. C. E. Matkovich and G. D. Christian, Anal. Chem., 1974, 46, 102.

    Article  CAS  Google Scholar 

  7. M. Tabata, M. Kumamoto, and J. Nishimoto, Anal. Chem., 1996, 68, 752.

    Article  Google Scholar 

  8. N. H. Chung and M. Tabata, Talanta, 2002, 58, 927.

    Article  CAS  PubMed  Google Scholar 

  9. S. S. Samaratunga, J. Nishimoto, and M. Tabata, Environ. Sci. Pollut. Res., 2008, 15, 27.

    Article  CAS  Google Scholar 

  10. X. Fu, J. Yu, and H. Liu, Water Sci. Technol., 2006, 53, 245.

    Google Scholar 

  11. J. G. Huddleston, H. D. Willauer, R. P. Swatloski, A. E. Visser, and R. D. Rogers, Chem. Commun., 1998, 1765.

  12. C. Reichardt and E. Harbusch-Görnert, Liebig Ann. Chem., 1983, 721.

  13. C. Reichardt, Chem. Rev., 1994, 94, 2319.

    Article  CAS  Google Scholar 

  14. M. J. Muldoon, C. M. Gordon, and I. R. Dunkin, J. Chem. Soc., Perkin Trans. 2, 2001, 433.

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Toho University, 2-2-1 Miyama, 274-8510, Funabashi, Japan

    Naoki Hirayama

  2. Research Center for Materials with Integrated Properties, Toho University, 2-2-1 Miyama, 274-8510, Funabashi, Japan

    Naoki Hirayama

  3. Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University, 920-1192, Kakuma-machi, Kanazawa, Japan

    Takaaki Higo

  4. Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University, 920-1192, Kakuma-machi, Kanazawa, Japan

    Hisanori Imura

Authors
  1. Naoki Hirayama
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Takaaki Higo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hisanori Imura
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Naoki Hirayama.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hirayama, N., Higo, T. & Imura, H. Evaluation of a Hydrophilic Ionic Liquid as a Salting-out Phase Separation Agent to a Water-Tetrahydrofuran Homogeneous System for Aqueous Biphasic Extraction Separation. ANAL. SCI. 28, 541–543 (2012). https://doi.org/10.2116/analsci.28.541

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2116/analsci.28.541

Search

Navigation